2020
Reform influences location of death: Interrupted time-series analysis on older adults and persons with dementia
Vroomen J, Kjellstadli C, Allore HG, van der Steen JT, Husebo B. Reform influences location of death: Interrupted time-series analysis on older adults and persons with dementia. PLOS ONE 2020, 15: e0241132. PMID: 33147248, PMCID: PMC7641450, DOI: 10.1371/journal.pone.0241132.Peer-Reviewed Original ResearchConceptsLocation of deathInterrupted time series analysisHome deathOlder adultsCoordination ReformNursing homesNursing home deathsAdults 65 yearsOlder adults 65 yearsHospital deathDeath RegistryNorwegian CausePrimary outcomeAdult decedentsDeath certificatesHospitalDementiaMortality dataCare infrastructureHome careDeathPopulation-level studiesAdultsPublic healthNumber of people
2015
Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study
Tinetti ME, McAvay G, Trentalange M, Cohen AB, Allore HG. Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study. The BMJ 2015, 351: h4984. PMID: 26432468, PMCID: PMC4591503, DOI: 10.1136/bmj.h4984.Peer-Reviewed Original ResearchConceptsSerotonin-norepinephrine reuptake inhibitorsMultiple chronic conditionsSelective serotonin reuptake inhibitorsAdjusted hazard ratioRisk of deathCalcium channel blockersChronic conditionsHazard ratioΒ-blockersCohort studyReuptake inhibitorsAtrial fibrillationOlder adultsChannel blockersCardiovascular drugsSSRIs/serotonin-norepinephrine reuptake inhibitorsRenin-angiotensin system blockersNorepinephrine reuptake inhibitorsSerotonin reuptake inhibitorsCommon combinationRAS blockersSystem blockersStudy drugHeart failureThromboembolic disease
2012
Contribution of Individual Diseases to Death in Older Adults with Multiple Diseases
Tinetti ME, McAvay GJ, Murphy TE, Gross CP, Lin H, Allore HG. Contribution of Individual Diseases to Death in Older Adults with Multiple Diseases. Journal Of The American Geriatrics Society 2012, 60: 1448-1456. PMID: 22734792, PMCID: PMC3419332, DOI: 10.1111/j.1532-5415.2012.04077.x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCause of DeathComorbidityFemaleGeriatricsHumansLongitudinal StudiesMaleConceptsOlder adultsSingle underlying causeRespiratory diseaseMedicare Current Beneficiary Survey participantsChronic lower respiratory diseasesUnderlying causeAcute kidney injuryLower respiratory diseaseAverage attributable fractionKidney injuryHazard ratioHeart failureLiver diseaseAcute eventMyocardial infarctionUnintentional injuriesAcute diseaseAttributable fractionNational representative sampleMedicare beneficiariesOlder adults' experiencesDiseaseIndividual diseasesDeathConfidence intervalsA method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome.
Lin H, Allore HG, McAvay G, Tinetti ME, Gill TM, Gross CP, Murphy TE. A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome. American Journal Of Public Health 2012, 103: 177-82. PMID: 22515873, PMCID: PMC3518339, DOI: 10.2105/ajph.2011.300458.Peer-Reviewed Original ResearchConceptsHealth outcomesAttributable fraction methodPrecipitating Events ProjectAdverse health outcomesMultiple diseasesAcute episodeNew onsetHeart failureAdverse outcomesRisk factorsAttributable fractionNew Haven CountyDiseaseIndividual diseasesOlder adultsOutcomesAdditive effectDeathEvent outcomesOnsetPneumoniaCohort
2010
Trajectories of Disability in the Last Year of Life
Gill TM, Gahbauer EA, Han L, Allore HG. Trajectories of Disability in the Last Year of Life. New England Journal Of Medicine 2010, 362: 1173-1180. PMID: 20357280, PMCID: PMC2877372, DOI: 10.1056/nejmoa0909087.Peer-Reviewed Original ResearchConceptsCourse of disabilityDisability trajectoriesOrgan failureAdvanced dementiaSudden deathOlder personsSevere disabilityCommunity-dwelling older personsTrajectories of disabilityLevel of disabilityCatastrophic disabilityEnd of lifeProgressive disabilityFunctional statusDeath certificatesCommon conditionBaseline assessmentPredominant trajectoriesMonthly interviewsDeathDisabilityLongitudinal studyDementiaFrailtyDecedents