2023
SEQUENCE ANALYSIS OF CARDIOMETABOLIC MULTIMORBIDITY AND ASSOCIATION WITH SUBSEQUENT DEMENTIA
Nagel C, Allore H, Botoseneanu A, Kaye J, Newsom J, Bishop N, Quiñones A. SEQUENCE ANALYSIS OF CARDIOMETABOLIC MULTIMORBIDITY AND ASSOCIATION WITH SUBSEQUENT DEMENTIA. Innovation In Aging 2023, 7: 230-231. PMCID: PMC10736019, DOI: 10.1093/geroni/igad104.0758.Peer-Reviewed Original ResearchIncident cardiometabolic diseaseCardiometabolic multimorbidityCardiometabolic diseasesMyocardial infarctionSubsequent dementiaHeart diseaseSelf-reported diagnosisAging Trends StudyBaseline diseasePrior diseaseIncident diseaseNational HealthMultimorbidityMultimorbidity researchDiseaseCognitive healthA Joint Model for Disability, Self-Rated Health, and Mortality Among Medicare Beneficiaries—Differences by Chronic Disease and Race/Ethnicity
Quiñones A, McAvay G, Vander Wyk B, Han L, Nagel C, Allore H. A Joint Model for Disability, Self-Rated Health, and Mortality Among Medicare Beneficiaries—Differences by Chronic Disease and Race/Ethnicity. Journal Of Aging And Health 2023, 36: 642-653. PMID: 37879084, PMCID: PMC11446605, DOI: 10.1177/08982643231210027.Peer-Reviewed Original ResearchPoor self-rated healthSelf-rated healthHigher oddsADL disabilityHip fractureAging Trends Study dataOlder adultsConcurrent riskPatient-centered outcomesLongitudinal logistic regression modelsLogistic regression modelsRace/ethnicityKidney diseaseChronic diseasesNational HealthDaily livingMortalityHealth declineOddsDisabilityHispanic respondentsDementiaDiseaseRiskWide variability
2022
Life course traumas and cardiovascular disease—the mediating role of accelerated aging
Cao X, Zhang J, Ma C, Li X, Kuo C, Levine ME, Hu G, Allore H, Chen X, Wu X, Liu Z. Life course traumas and cardiovascular disease—the mediating role of accelerated aging. Annals Of The New York Academy Of Sciences 2022, 1515: 208-218. PMID: 35725988, PMCID: PMC10145586, DOI: 10.1111/nyas.14843.Peer-Reviewed Original Research
2021
Racial and Ethnic Differences in Multimorbidity Changes Over Time
Quiñones AR, Newsom JT, Elman MR, Markwardt S, Nagel CL, Dorr DA, Allore HG, Botoseneanu A. Racial and Ethnic Differences in Multimorbidity Changes Over Time. Medical Care 2021, 59: 402-409. PMID: 33821829, PMCID: PMC8024615, DOI: 10.1097/mlr.0000000000001527.Peer-Reviewed Original ResearchConceptsMinimal diseaseOlder adultsProspective cohort studyHigher depressive symptomsMultimorbidity combinationsEthnic older adultsCohort studyMultimorbidity patternsLung diseaseHeart diseaseRetirement Study respondentsDelay progressionDepressive symptomsMultimorbidityDiseaseLatent class analysisLatent classesEthnic differencesWhite AmericansStudy respondentsMultinomial logistic modelAdultsClass analysisLogistic modelParticipants
2020
Individual Heterogeneity in the Probability of Hospitalization, Skilled Nursing Facility Admission, and Mortality
McAvay GJ, Vander Wyk B, Allore H. Individual Heterogeneity in the Probability of Hospitalization, Skilled Nursing Facility Admission, and Mortality. The Journals Of Gerontology Series A 2020, 76: 1668-1677. PMID: 33320184, PMCID: PMC8361334, DOI: 10.1093/gerona/glaa314.Peer-Reviewed Original ResearchConceptsSkilled nursing facility admissionsNursing facility admissionsChronic kidney diseaseHeart failureFacility admissionKidney diseaseChronic conditionsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseIschemic heart diseaseHealth care utilizationProbability of hospitalizationPulmonary diseaseCare utilizationMortality outcomesPoor outcomeHeart diseaseNational HealthOdds ratioDisease combinationsLongitudinal cohortSociodemographic factorsMedicaid ServicesDiseaseAging StudyAn Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer’s Disease and Related Dementia
Quiñones AR, Kaye J, Allore HG, Botoseneanu A, Thielke SM. An Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer’s Disease and Related Dementia. American Journal Of Alzheimer's Disease & Other Dementias® 2020, 35: 1533317520960874. PMID: 32969234, PMCID: PMC7984095, DOI: 10.1177/1533317520960874.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseEthnic disparitiesMultiple chronic diseasesMultimorbidity combinationsPoor outcomeAdverse outcomesChronic diseasesHigh burdenRelated dementiaClinical treatmentDiseaseADRDU.S. populationDementia researchMultimorbidityOutcomesBurdenRiskBroad effectsPopulationDementiaDisparitiesCareCaregivers
2012
Contribution of Individual Diseases to Death in Older Adults with Multiple Diseases
Tinetti ME, McAvay GJ, Murphy TE, Gross CP, Lin H, Allore HG. Contribution of Individual Diseases to Death in Older Adults with Multiple Diseases. Journal Of The American Geriatrics Society 2012, 60: 1448-1456. PMID: 22734792, PMCID: PMC3419332, DOI: 10.1111/j.1532-5415.2012.04077.x.Peer-Reviewed Original ResearchConceptsOlder adultsSingle underlying causeRespiratory diseaseMedicare Current Beneficiary Survey participantsChronic lower respiratory diseasesUnderlying causeAcute kidney injuryLower respiratory diseaseAverage attributable fractionKidney injuryHazard ratioHeart failureLiver diseaseAcute eventMyocardial infarctionUnintentional injuriesAcute diseaseAttributable fractionNational representative sampleMedicare beneficiariesOlder adults' experiencesDiseaseIndividual diseasesDeathConfidence intervalsA method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome.
Lin H, Allore HG, McAvay G, Tinetti ME, Gill TM, Gross CP, Murphy TE. A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome. American Journal Of Public Health 2012, 103: 177-82. PMID: 22515873, PMCID: PMC3518339, DOI: 10.2105/ajph.2011.300458.Peer-Reviewed Original ResearchConceptsHealth outcomesAttributable fraction methodPrecipitating Events ProjectAdverse health outcomesMultiple diseasesAcute episodeNew onsetHeart failureAdverse outcomesRisk factorsAttributable fractionNew Haven CountyDiseaseIndividual diseasesOlder adultsOutcomesAdditive effectDeathEvent outcomesOnsetPneumoniaCohort