2022
Temporal Trends in Racial and Ethnic Disparities in Multimorbidity Prevalence in the United States, 1999-2018
Caraballo C, Herrin J, Mahajan S, Massey D, Lu Y, Ndumele CD, Drye EE, Krumholz HM. Temporal Trends in Racial and Ethnic Disparities in Multimorbidity Prevalence in the United States, 1999-2018. The American Journal Of Medicine 2022, 135: 1083-1092.e14. PMID: 35472394, DOI: 10.1016/j.amjmed.2022.04.010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChronic DiseaseCross-Sectional StudiesEthnicityHumansMultimorbidityPrevalenceUnited StatesConceptsMultimorbidity prevalenceRace/ethnicityWhite individualsChronic conditionsBlack individualsSerial cross-sectional analysisCommon chronic conditionsRisk of morbidityPrevalence of multimorbidityPublic health interventionsCross-sectional analysisSelf-reported presenceSelf-reported raceLatino/HispanicMAIN OUTCOMEHealth interventionsEthnic disparitiesPrevalenceHealth inequalitiesStudy periodEarly lifeHispanic individualsTemporal trendsStudy sampleAsian individuals
2020
Cross‐sectional Analysis of Emergency Department and Acute Care Utilization Among Medicare Beneficiaries
Venkatesh AK, Mei H, Shuling L, D’Onofrio G, Rothenberg C, Lin Z, Krumholz HM. Cross‐sectional Analysis of Emergency Department and Acute Care Utilization Among Medicare Beneficiaries. Academic Emergency Medicine 2020, 27: 570-579. PMID: 32302034, DOI: 10.1111/acem.13971.Peer-Reviewed Original ResearchConceptsMultiple chronic conditionsEmergency departmentUnscheduled careMedicare beneficiariesCross-sectional analysisVisit ratesCare servicesHighest ED visit ratesNumber of EDVulnerable subpopulationsSkilled nursing facility useAmbulatory office settingNon-ED settingsUnscheduled care servicesAcute care utilizationED visit ratesOffice-based visitsAcute care servicesClaims-based definitionNursing facility useMedicare beneficiaries age 65Dual-eligible beneficiariesOlder adult populationBeneficiaries age 65Care visits
2018
Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States
Khera R, Valero-Elizondo J, Okunrintemi V, Saxena A, Das SR, de Lemos JA, Krumholz HM, Nasir K. Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States. JAMA Cardiology 2018, 3: 729-738. PMID: 29971325, PMCID: PMC6143078, DOI: 10.1001/jamacardio.2018.1813.Peer-Reviewed Original ResearchConceptsCatastrophic financial burdenLow-income familiesPocket health care expensesHigh financial burdenMedical Expenditure Panel SurveyHealth care expensesFamily incomeFinancial burdenPanel SurveyHealth expensesMean annual family incomePocket expensesCare expensesFinancial hardshipAtherosclerotic cardiovascular diseaseLow incomePocket health expensesAssociation of OutAnnual family incomeFederal poverty limitHigh-income familiesAnnual health expenditureLow-income adultsInsurance premiumsHealth expenditure
2017
The State of the Science on Integrating Palliative Care in Heart Failure
Gelfman L, Bakitas M, Warner Stevenson L, Kirkpatrick J, Goldstein N, Ahluwalia S, Allen L, Allen K, Arnold B, Bakitas M, Bekelman D, Buck H, Dionne-Odom J, Dougherty C, Dunbar S, Evangelista L, Fahlberg B, Fendler T, Gelfman L, Goldstein N, Hanson L, Hauptman P, Karlekar M, Kavalieratos D, Kirkpatrick J, Kirkwood P, Kono A, Krumholz H, Kutner J, Lala A, Lindenfeld J, Mancarella G, Matlock D, Matzo M, Maurer M, Morrison S, O'Donnell A, Pamboukian S, Pinney S, Prince S, Reigel B, Ritchie C, Rogers J, Spertus J, Steinhauser K, Stevenson L, Strömberg A, Sudore R, Swetz K, Teuteberg W, Teuteberg J, Tucker R, Tulsky J, Wiegand D. The State of the Science on Integrating Palliative Care in Heart Failure. Journal Of Palliative Medicine 2017, 20: 592-603. PMID: 29493362, PMCID: PMC5455612, DOI: 10.1089/jpm.2017.0178.Peer-Reviewed Original ResearchConceptsHeart failurePalliative careUncontrolled symptomsIntegrating Palliative CarePalliative care integrationAdvanced heart failureAdvanced HF patientsChronic progressive illnessLife-prolonging therapiesCare of patientsAdvance care planningQuality of careQuality of lifeHF diseaseHF patientsHealthcare utilizationProgressive illnessHF populationHigh morbidityInterdisciplinary careInterdisciplinary working groupCare planningLife careCurrent evidenceFamily caregivers
2016
Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over Time
Dharmarajan K, Qin L, Lin Z, Horwitz LI, Ross JS, Drye EE, Keshawarz A, Altaf F, Normand SL, Krumholz HM, Bernheim SM. Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over Time. Health Affairs 2016, 35: 1294-1302. PMID: 27385247, DOI: 10.1377/hlthaff.2015.1614.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCenters for Medicare and Medicaid Services, U.S.Chronic DiseaseDatabases, FactualDisease ProgressionFemaleGeriatric AssessmentHospital MortalityHumansIncidenceLength of StayMaleOutcome Assessment, Health CarePatient AdmissionPatient ReadmissionRetrospective StudiesRisk AssessmentSeverity of Illness IndexTime FactorsUnited States
2011
Trends in Comorbidity, Disability, and Polypharmacy in Heart Failure
Wong CY, Chaudhry SI, Desai MM, Krumholz HM. Trends in Comorbidity, Disability, and Polypharmacy in Heart Failure. The American Journal Of Medicine 2011, 124: 136-143. PMID: 21295193, PMCID: PMC3237399, DOI: 10.1016/j.amjmed.2010.08.017.Peer-Reviewed Original ResearchConceptsProportion of patientsHeart failureSelf-reported heart failureHeart failure populationComorbid chronic conditionsNumber of comorbiditiesNutrition Examination SurveyCare of patientsPrevalence of disabilityPhenotype of patientsComplexity of patientsMedication useRecent patientsFunctional disabilityExamination SurveyFailure populationPhysical functionPrescription medicationsPatient preferencesChronic conditionsNational HealthPatient's abilityComorbiditiesPatientsOlder individuals
2009
What Works In Chronic Care Management: The Case Of Heart Failure
Sochalski J, Jaarsma T, Krumholz HM, Laramee A, McMurray JJ, Naylor MD, Rich MW, Riegel B, Stewart S. What Works In Chronic Care Management: The Case Of Heart Failure. Health Affairs 2009, 28: 179-189. PMID: 19124869, DOI: 10.1377/hlthaff.28.1.179.Peer-Reviewed Original ResearchConceptsCare management programChronic care managementCare managementChronic care management programEvidence baseRoutine care patientsRandomized clinical trialsReadmission daysCare patientsHeart failureHospital readmissionClinical trialsPatient outcomesMulti-disciplinary teamHealth plansProgram delivery methodsPatientsImportant guidepostsManagement programDelivery methodsReadmissionTrials
2007
2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina
Fraker TD, Fihn SD, Gibbons R, Abrams J, Chatterjee K, Daley J, Deedwania P, Douglas J, Ferguson T, Gardin J, O'Rourke R, Williams S, Smith S, Jacobs A, Adams C, Anderson J, Buller C, Creager M, Ettinger S, Halperin J, Hunt S, Krumholz H, Kushner F, Lytle B, Nishimura R, Page R, Riegel B, Tarkington L, Yancy C. 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina. Journal Of The American College Of Cardiology 2007, 50: 2264-2274. PMID: 18061078, DOI: 10.1016/j.jacc.2007.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAngina PectorisCardiovascular AgentsChronic DiseaseDietExerciseHumansHypolipidemic AgentsLife Style2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina
Fraker TD, Fihn SD, Committee W, MEERS 2, Gibbons R, Abrams J, Chatterjee K, Daley J, Deedwania P, Douglas J, Ferguson T, Gardin JM, O’Rourke R, Pasternak R, Williams S, Smith S, Jacobs A, Adams C, Anderson J, Buller C, Creager M, Ettinger S, Halperin J, Hunt S, Krumholz H, Kushner F, Lytle B, Nishimura R, Page R, Riegel B, Tarkington L, Yancy C. 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina. Circulation 2007, 116: 2762-2772. PMID: 17998462, DOI: 10.1161/circulationaha.107.187930.Peer-Reviewed Original ResearchTelemonitoring for Patients With Chronic Heart Failure: A Systematic Review
Chaudhry SI, Phillips CO, Stewart SS, Riegel B, Mattera JA, Jerant AF, Krumholz HM. Telemonitoring for Patients With Chronic Heart Failure: A Systematic Review. Journal Of Cardiac Failure 2007, 13: 56-62. PMID: 17339004, PMCID: PMC1910700, DOI: 10.1016/j.cardfail.2006.09.001.BooksConceptsHeart failure patientsFailure patientsHeart failureHigh-risk heart failure patientsHigh-risk Hispanic populationMonitoring of signsChronic heart failureHeart failure hospitalizationLow-risk patientsDisease managementHigh-quality careFailure hospitalizationNegative studiesSymptom monitoringPatientsHealth statusMEDLINE databaseSystematic reviewQuality carePhysiologic monitoringIntervention typeEvidence baseSimilar effectivenessIntervention costsHispanic population
2006
The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening.
Gross CP, McAvay GJ, Krumholz HM, Paltiel AD, Bhasin D, Tinetti ME. The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Annals Of Internal Medicine 2006, 145: 646-53. PMID: 17088577, DOI: 10.7326/0003-4819-145-9-200611070-00006.Peer-Reviewed Original ResearchConceptsChronic illnessColorectal cancerChronic conditionsLife expectancyCancer stageEarly-stage colorectal cancerPopulation-based cancer registriesPatients 67 yearsRetrospective cohort studyStage I cancerAdministrative claims dataChronic condition groupsFinal study sampleYears of ageShort life expectancyCohort studyEffect of agePatient ageI cancerCancer RegistryCancer variesHealthy patientsIndividual patientsMedicare claimsAdministrative claimsImpact of Chronic Kidney Disease on Health-Related Quality-of-Life Improvement After Coronary Artery Bypass Surgery
Parikh CR, Coca SG, Smith GL, Vaccarino V, Krumholz HM. Impact of Chronic Kidney Disease on Health-Related Quality-of-Life Improvement After Coronary Artery Bypass Surgery. JAMA Internal Medicine 2006, 166: 2014-2019. PMID: 17030836, DOI: 10.1001/archinte.166.18.2014.Peer-Reviewed Original ResearchConceptsSevere chronic kidney diseaseChronic kidney diseasePhysical functionMH scorePF scoresKidney diseaseMedical Outcomes Trust Short FormAdvanced chronic kidney diseaseCoronary artery bypass surgeryLife outcomesCoronary artery bypassPrimary end pointArtery bypass surgeryHealth-related qualityCoronary artery diseaseMH subscalesArtery bypassCKD stageBypass surgeryArtery diseaseHealth SurveyMean changeStage 0Mean decreaseCABG
2005
ACC/AHA Clinical Performance Measures for Adults With Chronic Heart Failure
Bonow RO, Bennett S, Casey DE, Ganiats TG, Hlatky MA, Konstam MA, Lambrew CT, Normand SL, Pina IL, Radford MJ, Smith AL, Stevenson LW, Bonow R, Bennett S, Burke G, Eagle K, Krumholz H, Lambrew C, Linderbaum J, Masoudi F, Normand S, Ritchie J, Rumsfeld J, Spertus J. ACC/AHA Clinical Performance Measures for Adults With Chronic Heart Failure. Circulation 2005, 112: 1853-1887. PMID: 16160201, DOI: 10.1161/circulationaha.105.170072.Peer-Reviewed Original ResearchACC/AHA Clinical Performance Measures for Adults With Chronic Heart Failure A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Heart Failure Clinical Performance Measures) Endorsed by the Heart Failure Society of America
Bonow RO, Bennett S, Casey DE, Ganiats TG, Hlatky MA, Konstam MA, Lambrew CT, Normand SL, Piña IL, Radford MJ, Smith AL, Stevenson LW, Bonow RO, Bennett SJ, Burke G, Eagle KA, Krumholz HM, Lambrew CT, Linderbaum J, Masoudi FA, Normand SL, Ritchie JL, Rumsfeld JS, Spertus JA. ACC/AHA Clinical Performance Measures for Adults With Chronic Heart Failure A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Heart Failure Clinical Performance Measures) Endorsed by the Heart Failure Society of America. Journal Of The American College Of Cardiology 2005, 46: 1144-1178. PMID: 16168305, DOI: 10.1016/j.jacc.2005.07.012.Peer-Reviewed Original Research
1998
Resuscitation Preferences Among Patients With Severe Congestive Heart Failure
Krumholz H, Phillips R, Hamel M, Teno J, Bellamy P, Broste S, Califf R, Vidaillet H, Davis R, Muhlbaier L, Connors A, Lynn J, Goldman L. Resuscitation Preferences Among Patients With Severe Congestive Heart Failure. Circulation 1998, 98: 648-655. PMID: 9715857, DOI: 10.1161/01.cir.98.7.648.Peer-Reviewed Original ResearchConceptsSevere congestive heart failureCongestive heart failureResuscitation preferencesHeart failurePhysicians' perceptionsPatient preferencesMonths of dischargePoor functional statusQuarter of patientsSevere heart failureDiscussion of preferencesWorse prognosisFunctional statusPatientsOlder agePhysiciansSubstantial proportionSignificant correlatesResuscitationMonthsHigh agreementFailureHigher incomeExacerbationPrognosis