2017
Sex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial Infarction
Dreyer RP, Dharmarajan K, Kennedy KF, Jones PG, Vaccarino V, Murugiah K, Nuti SV, Smolderen KG, Buchanan DM, Spertus JA, Krumholz HM. Sex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial Infarction. Circulation 2017, 135: 521-531. PMID: 28153989, PMCID: PMC5312975, DOI: 10.1161/circulationaha.116.024993.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAge-sex interactionHigh riskRehospitalization ratesClinical factorsMyocardial infarctionCox proportional hazards modelSignificant age-sex interactionCause rehospitalization rateSex differencesMedical record abstractionProportional hazards modelYears of ageFirst yearTRIUMPH studyCause rehospitalizationRecord abstractionPatient interviewsRehospitalizationUS CentersHazards modelPsychosocial factorsPhysician panelHealth statusPsychosocial state
2011
Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH)
Arnold SV, Chan PS, Jones PG, Decker C, Buchanan DM, Krumholz HM, Ho PM, Spertus JA. Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH). Circulation Cardiovascular Quality And Outcomes 2011, 4: 467-476. PMID: 21772003, PMCID: PMC3376532, DOI: 10.1161/circoutcomes.110.960468.Peer-Reviewed Original ResearchConceptsHealth status studiesMyocardial infarctionHealth statusPostdischarge careAcute Myocardial Infarction Patients' Health StatusSubset of patientsTranslational researchPost-MI outcomesRacial differencesHigh mortality ratePatients' health statusMI registryChart abstractionHospital dischargeWhite patientsBlack patientsVital statusMedical historyWorse outcomesTreatment characteristicsInpatient careBaseline interviewUS CentersBlood samplesPatients
2009
Increased Mortality among Survivors of Myocardial Infarction with Kidney Dysfunction: the Contribution of Gaps in the use of Guideline-Based Therapies
Peterson PN, Ambardekar AV, Jones PG, Krumholz HM, Schelbert E, Spertus JA, Rumsfeld JS, Masoudi FA. Increased Mortality among Survivors of Myocardial Infarction with Kidney Dysfunction: the Contribution of Gaps in the use of Guideline-Based Therapies. BMC Cardiovascular Disorders 2009, 9: 29. PMID: 19586550, PMCID: PMC2716301, DOI: 10.1186/1471-2261-9-29.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedFemaleGlomerular Filtration RateHumansKaplan-Meier EstimateKidney DiseasesMaleMiddle AgedMyocardial InfarctionPractice Guidelines as TopicProportional Hazards ModelsProspective StudiesRegistriesRisk AssessmentSeverity of Illness IndexSurvivorsTime FactorsTreatment OutcomeUnited StatesConceptsGlomerular filtration rateAcute myocardial infarctionGuideline-based medical therapyGuideline-based therapyMedical therapyKidney dysfunctionMyocardial infarctionUse of guidelinesEligible patientsRenal dysfunctionHazard ratioCox regressionPathophysiological abnormalitiesClinical variablesKidney diseaseFiltration rateNovel therapiesUS CentersHigh mortalityPatientsTherapyFurther adjustmentMortalityDysfunctionTreatment factors
2007
Acute Noncardiac Conditions and In-Hospital Mortality in Patients With Acute Myocardial Infarction
Lichtman JH, Spertus JA, Reid KJ, Radford MJ, Rumsfeld JS, Allen NB, Masoudi FA, Weintraub WS, Krumholz HM. Acute Noncardiac Conditions and In-Hospital Mortality in Patients With Acute Myocardial Infarction. Circulation 2007, 116: 1925-1930. PMID: 17923572, DOI: 10.1161/circulationaha.107.722090.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNoncardiac conditionsHospital mortalityMyocardial infarctionConcomitant conditionsCommon concomitant conditionsHours of admissionIn-Hospital MortalityMedical record reviewTime of admissionEvidence-based therapiesClinical characteristicsHospital admissionMultivariable analysisRecord reviewSevere pneumoniaPrognostic importanceUS CentersInfarctionDisease severityPatientsAdmissionMortalityStudy sampleMarked increase
2006
The Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER)—Evaluating the impact of myocardial infarction on patient outcomes
Spertus JA, Peterson E, Rumsfeld JS, Jones PG, Decker C, Krumholz H, Consortium C. The Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER)—Evaluating the impact of myocardial infarction on patient outcomes. American Heart Journal 2006, 151: 589-597. PMID: 16504619, DOI: 10.1016/j.ahj.2005.05.026.Peer-Reviewed Original ResearchConceptsHealth status outcomesMyocardial infarctionChart abstractionPostdischarge careMI carePatients' health status outcomesDetailed chart abstractionOutcomes of patientsHealth status characteristicsOne-month followPatient-centered interviewProspective registryLongitudinal careMedical historyPatient outcomesInpatient careUS CentersPatientsStatus outcomesNovel registryHealth statusQuality careInfarctionCarePREMIER study