2010
Discontinuation of Antihyperglycemic Therapy and Clinical Outcomes After Acute Myocardial Infarction in Older Patients With Diabetes
Lipska KJ, Wang Y, Kosiborod M, Masoudi FA, Havranek EP, Krumholz HM, Inzucchi SE. Discontinuation of Antihyperglycemic Therapy and Clinical Outcomes After Acute Myocardial Infarction in Older Patients With Diabetes. Circulation Cardiovascular Quality And Outcomes 2010, 3: 236-242. PMID: 20354220, DOI: 10.1161/circoutcomes.109.887620.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAntihyperglycemic therapyAntihyperglycemic agentsOlder patientsMyocardial infarctionMortality rateMultivariable Cox proportional hazards modelsCox proportional hazards modelFrequency of discontinuationGlucose-lowering agentsGlucose-lowering therapyInclusion/exclusion criteriaProportional hazards modelYear of dischargeHigh mortality rateDiabetic regimenFirst rehospitalizationReadmission ratesSecondary outcomesHeart failurePrimary outcomeClinical outcomesMultivariable analysisRetrospective studyIndependent association
2005
Insulin-Sensitizing Antihyperglycemic Drugs and Mortality After Acute Myocardial Infarction
Inzucchi SE, Masoudi FA, Wang Y, Kosiborod M, Foody JM, Setaro JF, Havranek EP, Krumholz HM. Insulin-Sensitizing Antihyperglycemic Drugs and Mortality After Acute Myocardial Infarction. Diabetes Care 2005, 28: 1680-1689. PMID: 15983320, DOI: 10.2337/diacare.28.7.1680.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYear of dischargeHeart failureAntihyperglycemic agentsMyocardial infarctionHigh riskDiabetic patientsInsulin sensitizersMultivariable Cox proportional hazards modelsCox proportional hazards modelBorderline higher riskOlder diabetic patientsRetrospective cohort studyHeart failure readmissionInsulin-sensitizing drugsProportional hazards modelFirst rehospitalizationCause readmissionCohort studySecondary outcomesDischarge prescriptionsPrimary outcomeMultivariable analysisAntihyperglycemic drugsIndependent association