2006
Lim kinase regulates the development of olfactory and neuromuscular synapses
Ang LH, Chen W, Yao Y, Ozawa R, Tao E, Yonekura J, Uemura T, Keshishian H, Hing H. Lim kinase regulates the development of olfactory and neuromuscular synapses. Developmental Biology 2006, 293: 178-190. PMID: 16529736, DOI: 10.1016/j.ydbio.2006.01.030.Peer-Reviewed Original ResearchConceptsLIM kinaseSerine/threonine kinaseP21-activated kinaseCofilin functionMolecular functionsActin cytoskeletonThreonine kinaseDownstream effectorsLIMK1 geneVivo functionSynapse developmentCritical regulatorLIMKKinaseGenesPotent regulatorDevelopment of olfactoryEctopic glomeruliAntennal lobeGlomerular developmentRegulatorBiochemical actionsNeuromuscular synapsesNeuromuscular junctionSynaptic boutons
2005
Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit
Mosca TJ, Carrillo RA, White BH, Keshishian H. Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 3477-3482. PMID: 15728380, PMCID: PMC552910, DOI: 10.1073/pnas.0406164102.Peer-Reviewed Original ResearchConceptsNeuromuscular junctionPostsynaptic membrane excitabilityChannel subunitsActivity-dependent changesPotassium channel subunitsPostsynaptic potentialsNervous system developmentNeuronal excitabilityArbor growthIA currentsPostsynaptic partnersArbor sizeNeurotransmitter releaseMembrane excitabilityLarval neuromuscular junctionElectrical excitabilityExcitabilityElectrical activityBehavioral phenotypesMuscleSh mutationsMorphological changesPhenotypeMotoneuronsNeurons