Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit
Mosca TJ, Carrillo RA, White BH, Keshishian H. Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 3477-3482. PMID: 15728380, PMCID: PMC552910, DOI: 10.1073/pnas.0406164102.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedBehavior, AnimalDrosophilaDrosophila ProteinsPhenotypePotassium ChannelsShaker Superfamily of Potassium ChannelsSynapsesConceptsNeuromuscular junctionPostsynaptic membrane excitabilityChannel subunitsActivity-dependent changesPotassium channel subunitsPostsynaptic potentialsNervous system developmentNeuronal excitabilityArbor growthIA currentsPostsynaptic partnersArbor sizeNeurotransmitter releaseMembrane excitabilityLarval neuromuscular junctionElectrical excitabilityExcitabilityElectrical activityBehavioral phenotypesMuscleSh mutationsMorphological changesPhenotypeMotoneuronsNeurons