2016
Cortical superficial siderosis predicts early recurrent lobar hemorrhage
Roongpiboonsopit D, Charidimou A, William CM, Lauer A, Falcone GJ, Martinez-Ramirez S, Biffi A, Ayres A, Vashkevich A, Awosika OO, Rosand J, Gurol ME, Silverman SB, Greenberg SM, Viswanathan A. Cortical superficial siderosis predicts early recurrent lobar hemorrhage. Neurology 2016, 87: 1863-1870. PMID: 27694268, PMCID: PMC5100711, DOI: 10.1212/wnl.0000000000003281.Peer-Reviewed Original ResearchConceptsCortical superficial siderosisConvexity subarachnoid hemorrhageCerebral amyloid angiopathyRecurrent ICHSuperficial siderosisAcute convexity subarachnoid hemorrhageDisseminated cortical superficial siderosisSingle-center cohort studyBaseline ICH volumeRecurrent lobar hemorrhageProportional hazards modelWhite matter hyperintensitiesIntracerebral hemorrhage recurrenceLobar hemorrhageLobar ICHSymptomatic ICHBoston criteriaConsecutive survivorsCohort studyAmyloid angiopathyHemorrhage recurrenceIndependent predictorsUnivariable analysisCerebral microbleedsIndex event
2014
Interrelationship of superficial siderosis and microbleeds in cerebral amyloid angiopathy
Shoamanesh A, Martinez-Ramirez S, Oliveira-Filho J, Reijmer Y, Falcone GJ, Ayres A, Schwab K, Goldstein JN, Rosand J, Gurol ME, Viswanathan A, Greenberg SM. Interrelationship of superficial siderosis and microbleeds in cerebral amyloid angiopathy. Neurology 2014, 83: 1838-1843. PMID: 25320098, PMCID: PMC4240429, DOI: 10.1212/wnl.0000000000000984.Peer-Reviewed Original ResearchConceptsCortical superficial siderosisCerebral amyloid angiopathyCMB countCerebral microbleedsSuperficial siderosisAmyloid angiopathyΕ4 allele frequencyCross-sectional analysisCSS presenceAPOE genotypeAPOE ε4MRI scansAngiopathyMicrobleedsSiderosisCountSeverityGenetic associationLongitudinal research studyCS relativeDistinct patternsAllele frequenciesSubjectsIndividualsTertile