2020
Statin treatment and cerebral microbleeds: A systematic review and meta-analysis
Katsanos AH, Lioutas VA, Charidimou A, Catanese L, Ng KKH, Perera K, Boasquevisque D, Falcone GJ, Sheth KN, Romero JR, Tsivgoulis G, Smith EE, Sharma M, Selim MH, Shoamanesh A, Initiative T. Statin treatment and cerebral microbleeds: A systematic review and meta-analysis. Journal Of The Neurological Sciences 2020, 420: 117224. PMID: 33183779, DOI: 10.1016/j.jns.2020.117224.Peer-Reviewed Original ResearchConceptsCMB presenceStatin useCurrent statin useStatin treatmentRandomized-controlled clinical trialSpontaneous intracerebral hemorrhageRandom-effects modelCMB prevalenceIschemic strokeHemorrhagic strokeAdjusted analysisCerebral microbleedsIntracerebral hemorrhageRandomized trialsUnadjusted analysesClinical trialsEligible studiesAncillary studiesObservational studyPooled estimatesGeneral populationSystematic reviewUnadjusted probabilitySystematic searchCross-sectional data
2015
Intakes of caffeine, coffee and tea and risk of amyotrophic lateral sclerosis: Results from five cohort studies
Fondell E, O’Reilly É, Fitzgerald KC, Falcone GJ, Kolonel LN, Park Y, Gapstur SM, Ascherio A. Intakes of caffeine, coffee and tea and risk of amyotrophic lateral sclerosis: Results from five cohort studies. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2015, 16: 366-371. PMID: 25822002, PMCID: PMC4589421, DOI: 10.3109/21678421.2015.1020813.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisMultivariable-adjusted risk ratiosALS riskRisk ratioCohort studyLateral sclerosisCases of ALSCox proportional hazards regressionProportional hazards regressionLarge cohort studyIntake of caffeineAdenosine A2A receptorsRandom-effects modelConsumption of caffeineHazards regressionALS incidenceLowest quintileMotor neuronsCaffeine intakeA2A receptorsAssociation of caffeineLarger studyIntakeSclerosisRisk
2014
Dietary Fiber and Amyotrophic Lateral Sclerosis: Results From 5 Large Cohort Studies
Fondell E, O'Reilly É, Fitzgerald KC, Falcone GJ, Kolonel LN, Park Y, McCullough ML, Ascherio A. Dietary Fiber and Amyotrophic Lateral Sclerosis: Results From 5 Large Cohort Studies. American Journal Of Epidemiology 2014, 179: 1442-1449. PMID: 24816788, PMCID: PMC4051879, DOI: 10.1093/aje/kwu089.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisCohort studyALS riskFiber intakeLateral sclerosisCause of ALSLarge prospective cohort studyRisk of ALSProspective cohort studyHigh fiber intakeMedian survival timeCase-control studyLarge cohort studyProportional hazards modelCohort-specific estimatesRandom-effects modelInflammatory markersProspective studyHighest quintileALS casesDietary intakeCereal fiberSurvival timeLower riskHazards model
2013
Magnesium intake and risk of amyotrophic lateral sclerosis: Results from five large cohort studies
Fondell E, O’Reilly É, Fitzgerald KC, Falcone GJ, McCullough ML, Park Y, Kolonel LN, Ascherio A. Magnesium intake and risk of amyotrophic lateral sclerosis: Results from five large cohort studies. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2013, 14: 356-361. PMID: 23777266, PMCID: PMC3743429, DOI: 10.3109/21678421.2013.803577.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisMagnesium intakeALS riskCohort studyLateral sclerosisCases of ALSLarge prospective cohort studyProspective cohort studyDietary magnesium intakeLow magnesium intakeCase-control studyLarge cohort studyProportional hazards modelCohort-specific estimatesRandom-effects modelProspective studyHighest quintileDietary intakeProtective effectHazards modelIntakeMagnesium absorptionSclerosisHeavy metal exposureRisk
2012
Premorbid body mass index and risk of amyotrophic lateral sclerosis
O'Reilly ÉJ, Wang H, Weisskopf MG, Fitzgerald KC, Falcone G, McCullough ML, Thun M, Park Y, Kolonel LN, Ascherio A. Premorbid body mass index and risk of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2012, 14: 205-211. PMID: 23134505, PMCID: PMC3615420, DOI: 10.3109/21678421.2012.735240.Peer-Reviewed Original ResearchConceptsBody mass indexHealthy body mass indexPremorbid body mass indexALS ratesMass indexCohort-specific Cox proportional hazard modelsLower premorbid Body Mass IndexLower body mass indexCox proportional hazards modelAmyotrophic lateral sclerosis riskProportional hazards modelAmyotrophic lateral sclerosisRandom-effects modelOngoing cohortUnhealthy weightLateral sclerosisHazards modelUndiagnosed diseaseCurrent weightWeight lossObeseALSAssociationMalesFemalesNon-steroidal anti-inflammatory drugs and amyotrophic lateral sclerosis: Results from five prospective cohort studies
Fondell E, O'Reilly ÉJ, Fitzgerald KC, Falcone GJ, McCullough ML, Thun MJ, Park Y, Kolonel LN, Ascherio A. Non-steroidal anti-inflammatory drugs and amyotrophic lateral sclerosis: Results from five prospective cohort studies. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2012, 13: 573-579. PMID: 22871075, PMCID: PMC3474335, DOI: 10.3109/17482968.2012.703209.Peer-Reviewed Original ResearchConceptsNon-steroidal anti-inflammatory drugsProspective cohort studyNSAID useALS riskAnti-inflammatory drugsCohort studyNon-aspirin NSAID useNon-aspirin NSAID usersAmyotrophic lateral sclerosis (ALS) pathologyLarge prospective cohort studyProportional hazards modelAmyotrophic lateral sclerosisCohort-specific estimatesRandom-effects modelAspirin useNSAID usersProspective dataRelative riskPathological studiesLateral sclerosisHazards modelRiskEffects modelDrugsOverall effect