1999
Structural and functional brain changes in bipolar disorder: a selective review
Pearlson G. Structural and functional brain changes in bipolar disorder: a selective review. Schizophrenia Research 1999, 39: 133-140. PMID: 10507524, DOI: 10.1016/s0920-9964(99)00112-7.Peer-Reviewed Original ResearchMeSH KeywordsAffective SymptomsBipolar DisorderBrainBrain InjuriesHumansNeural PathwaysSchizophrenia
1987
Mania After Brain Injury: A Controlled Study of Causative Factors
Starkstein S, Pearlson G, Boston J, Robinson R. Mania After Brain Injury: A Controlled Study of Causative Factors. JAMA Neurology 1987, 44: 1069-1073. PMID: 3632381, DOI: 10.1001/archneur.1987.00520220065019.Peer-Reviewed Original ResearchConceptsBrain injuryVentricle/brain ratiosPossible family historyFocal brain injurySecondary maniaRight hemisphere lesionsSubcortical atrophyBrain ratioDepressive episodeLimbic areasManic patientsFamily historyManic syndromeFocal lesionsAffective disordersPatientsInjuryLesionsCausative factorsRare occurrenceHemisphere lesionsGenetic loadingRight hemisphereManiaRight hemisphere involvement
1985
Symptomatic, Familial, Perinatal, and Social Correlates of Computerized Axial Tomography (CAT) Changes in Schizophrenics and Bipolars
PEARLSON G, GARBACZ D, MOBERG P, AHN H, DEPAULO J. Symptomatic, Familial, Perinatal, and Social Correlates of Computerized Axial Tomography (CAT) Changes in Schizophrenics and Bipolars. The Journal Of Nervous And Mental Disease 1985, 173: 42-50. PMID: 3965611, DOI: 10.1097/00005053-198501000-00007.Peer-Reviewed Original ResearchConceptsVentricular enlargementFamily historyNegative symptomsComputerized axial tomography scanLateral ventricular enlargementAxial tomography scanPast psychiatric historyEarly brain damageMarked ventricular enlargementSubgroup of schizophrenicsPoor premorbid adjustmentLateral ventricularTomography changesBrain ratioPatient groupBrain damageTomography scanPsychiatric illnessPsychiatric historyBipolar patientsNormal controlsEarly onsetPatientsPremorbid adjustmentSignificant proportion
1983
Mood Change following Bilateral Hemisphere Brain Injury
Lipsey J, Robinson R, Pearlson G, Rao K, Price T. Mood Change following Bilateral Hemisphere Brain Injury. The British Journal Of Psychiatry 1983, 143: 266-273. PMID: 6626839, DOI: 10.1192/bjp.143.3.266.Peer-Reviewed Original ResearchConceptsHemisphere brain injuryFunctional physical impairmentBrain injuryCognitive impairmentPhysical impairmentLeft frontal lobe lesionFrontal lobe lesionsThromboembolic strokeBrain lesionsSuch injuriesCT scanLesion locationDepression severityLobe lesionsLesion proximityDepressive symptomatologyLesion ageFrontal poleInjuryMood changesPatientsImpairmentMood ScaleLesionsDepression