2023
Characterization of the extracellular free water signal in schizophrenia using multi-site diffusion MRI harmonization
Cetin-Karayumak S, Lyall A, Di Biase M, Seitz-Holland J, Zhang F, Kelly S, Elad D, Pearlson G, Tamminga C, Sweeney J, Clementz B, Schretlen D, Stegmayer K, Walther S, Lee J, Crow T, James A, Voineskos A, Buchanan R, Szeszko P, Malhotra A, Keshavan M, Shenton M, Rathi Y, Pasternak O, Kubicki M. Characterization of the extracellular free water signal in schizophrenia using multi-site diffusion MRI harmonization. Molecular Psychiatry 2023, 28: 2030-2038. PMID: 37095352, PMCID: PMC11146151, DOI: 10.1038/s41380-023-02068-1.Peer-Reviewed Original ResearchDuration of illnessIllness stageHealthy controlsWhole brain white matterDifferent illness stagesFree-water imagingSchizophrenia spectrum disordersYounger patientsBrain white matterExtracellular free waterProlonged illnessEarly psychosisDiffusion magnetic resonanceWhite matterDemographic dataIllnessSchizophreniaSmall effect sizesShort durationTime courseAgeEffect sizeSignificant global increaseInternational sitesDisorders
2001
Regional cortical white matter reductions in velocardiofacial syndrome: a volumetric MRI analysis
Kates W, Burnette C, Jabs E, Rutberg J, Murphy A, Grados M, Geraghty M, Kaufmann W, Pearlson G. Regional cortical white matter reductions in velocardiofacial syndrome: a volumetric MRI analysis. Biological Psychiatry 2001, 49: 677-684. PMID: 11313035, DOI: 10.1016/s0006-3223(00)01002-7.Peer-Reviewed Original ResearchConceptsWhite matter reductionLobar brain regionsVelocardiofacial syndromeWhite matterBrain regionsVolumetric MRI analysisWhite matter anomaliesWhite matter volumeMatter reductionCerebral lobesAxonal integrityPsychiatric disordersCardiac defectsMatter volumeSyndromeBrain tissueGray matterLobar volumesCSF compartmentMRI analysisBrain developmentCraniofacial anomaliesUnaffected childrenNeuropsychiatric phenotypesCoronal images