2020
O3.4. PSYCHOSIS PHENOTYPES FROM B-SNIP FOR CLINICAL ADVANCES: BIOTYPE CHARACTERISTICS AND TARGETS
Clementz B, Trotti R, Pearlson G, Keshavan M, Gershon E, Keedy S, Ivleva E, McDowell J, Tamminga C. O3.4. PSYCHOSIS PHENOTYPES FROM B-SNIP FOR CLINICAL ADVANCES: BIOTYPE CHARACTERISTICS AND TARGETS. Schizophrenia Bulletin 2020, 46: s7-s7. PMCID: PMC7234003, DOI: 10.1093/schbul/sbaa028.015.Peer-Reviewed Original ResearchClinical featuresPsychosis biotypesPsychosis casesPsychosis syndromeTreatment targetsSpecific treatment targetsB-SNIPClinical manifestationsBiomarker profilesPsychosis subgroupsB-SNIP consortiumDeep phenotyping approachPathophysiological mechanismsPsychosis patientsBipolar-Schizophrenia NetworkPsychosis diagnosisBiological subtypesHealthy personsClinical practiceClinical advancesNegative symptomsClinical phenomenologySyndrome
2017
SA64. Hallucination Severity Predicted by Auditory Cortex Resting State Connectivity in Bipolar and Schizophrenia Network on Intermediate Phenotypes Study
Okuneye V, Meda S, Keshavan M, Sweeney J, Tamminga C, Pearlson G, Gershon E, Keedy S. SA64. Hallucination Severity Predicted by Auditory Cortex Resting State Connectivity in Bipolar and Schizophrenia Network on Intermediate Phenotypes Study. Schizophrenia Bulletin 2017, 43: s136-s136. PMCID: PMC5475960, DOI: 10.1093/schbul/sbx023.063.Peer-Reviewed Original ResearchAuditory cortexHallucination severityState connectivityPsychosis patientsSignificant negative associationIntermediate Phenotypes (B-SNIP) studySchizophrenia NetworkResting-state connectivityAbnormal activation patternsBrodmann area 22Primary auditory cortexSecondary auditory cortexRight orbitofrontal cortexPrevious functional imaging studiesPhenotype studiesClinical rating scalesAuditory processing areasPossible common pathwayFunctional imaging studiesMiddle temporal cortexNegative associationPsychosis subjectsHealthy controlsHealthy subjectsConnectivity dysfunction