2023
A Comprehensive Primer on Radiation Oncology for Non-Radiation Oncologists
Beddok A, Lim R, Thariat J, Shih H, Fakhri G. A Comprehensive Primer on Radiation Oncology for Non-Radiation Oncologists. Cancers 2023, 15: 4906. PMID: 37894273, PMCID: PMC10605284, DOI: 10.3390/cancers15204906.Peer-Reviewed Original ResearchProton therapyRadiation therapyRadiation oncologistsIntensity-modulated proton therapyNon-oncologistsNon-radiation oncologistsImage-guided RTFollow-upExternal beam therapyArc therapyThree-dimensional conformal RTCT simulationPatient alignmentTarget volumeIntensity-modulated RTRT planningCompletion of RTPotential late effects of treatmentMedical physicistsLifelong follow-upLate effects of treatmentPatient follow-upBeam therapyNon-radiativeOptimize treatment outcomes
2016
Investigation of cone-beam CT image quality trade-off for image-guided radiation therapy
Bian J, Sharp G, Park Y, Ouyang J, Bortfeld T, Fakhri G. Investigation of cone-beam CT image quality trade-off for image-guided radiation therapy. Physics In Medicine And Biology 2016, 61: 3317-3346. PMID: 27032676, DOI: 10.1088/0031-9155/61/9/3317.Peer-Reviewed Original ResearchConceptsImage-guided radiation therapyCone-beam CTFiltered-backprojectionImage quality trade-offConventional filtered-backprojectionShort-scan reconstructionsFiltered-backprojection algorithmFan-beam reconstructionTV-based algorithmIterative reconstruction algorithmCatphan phantomRadiation therapyAngular rangeTotal-variationOptimal exposure levelClinical scannerScanning configurationReconstruction algorithmImaging conditionsCatphanPhantomExposure levelsTherapyConfigurationRange
2015
Improved Local Tumor Control With Supplementary Dose of Radiation Guided by 18F-FDG PET Soon After Standard Dose Radiation Therapy and Concurrent Chemotherapy in Inoperable Stages II and III Non-Small Cell Lung Cancer
Choi N, Gainor J, Ackman J, Lim R, Sharp G, Fakhri G, Niemierko A. Improved Local Tumor Control With Supplementary Dose of Radiation Guided by 18F-FDG PET Soon After Standard Dose Radiation Therapy and Concurrent Chemotherapy in Inoperable Stages II and III Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e438-e439. DOI: 10.1016/j.ijrobp.2015.07.1664.Peer-Reviewed Original ResearchMonitoring proton therapy with PET
Paganetti H, Fakhri G. Monitoring proton therapy with PET. British Journal Of Radiology 2015, 88: 20150173. PMID: 25989699, PMCID: PMC4628541, DOI: 10.1259/bjr.20150173.Peer-Reviewed Original ResearchConceptsPatient set-upDose conformityDose shapingInterfractional changesProton beamBeam deliveryDose calculationProton therapyTumor coveragePhotonic techniquesTreatment volumeTotal energyPatient anatomyBeamRadiation therapyProtonPatientsTherapyReduced total energyDoseSet-upRangeCalculationsRadiationEnergy
2014
Preliminary Investigation of CBCT Imaging Optimization for Image-Guided Radiation Therapy
Bian J, Sharp G, Park Y, Bortfeld T, Fakhri G. Preliminary Investigation of CBCT Imaging Optimization for Image-Guided Radiation Therapy. 2014, 1-4. DOI: 10.1109/nssmic.2014.7430871.Peer-Reviewed Original ResearchImage-guided radiation therapyCone-beam CTCone-beam CT image qualityImprove CBCT image qualityCBCT image qualityCone-beam CT imagesOptimization-based reconstruction algorithmsReduce patient doseImage qualityCBCT dataImages of improved qualityImaging doseReconstruction algorithmIterative reconstruction techniqueASD-POCSImage reconstruction algorithmPatient doseImprove image qualityRadiation therapyDose reductionRadiation doseImage-guidedDosePoor image qualityExposure levels
2012
In Vivo Treatment Verification Using In-room PET in Proton Radiation Therapy: First Clinical Trials and Evaluation of Short-length Scan
Min C, Zhu X, Winey B, Grogg K, Fakhri G, Bortfeld T, Paganetti H, Shih H. In Vivo Treatment Verification Using In-room PET in Proton Radiation Therapy: First Clinical Trials and Evaluation of Short-length Scan. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s53-s54. DOI: 10.1016/j.ijrobp.2012.07.347.Peer-Reviewed Original Research