1988
THE FREQUENCY OF EPSTEIN-BARR VIRUS INFECTION AND ASSOCIATED LYMPHOPROLIFERATIVE SYNDROME AFTER TRANSPLANTATION AND ITS MANIFESTATIONS IN CHILDREN
Ho M, Jaffe R, Miller G, Breinig M, Dummer J, Makowka L, Atchison R, Karrer F, Nalesnik M, Starzl T. THE FREQUENCY OF EPSTEIN-BARR VIRUS INFECTION AND ASSOCIATED LYMPHOPROLIFERATIVE SYNDROME AFTER TRANSPLANTATION AND ITS MANIFESTATIONS IN CHILDREN. Transplantation 1988, 45: 719-726. PMID: 2833828, PMCID: PMC2993427, DOI: 10.1097/00007890-198804000-00011.Peer-Reviewed Original ResearchConceptsLymphoproliferative syndromePrimary infectionEBV infectionTransplant recipientsEpstein-Barr virus infectionMonoclonal B-cell lymphomaPediatric liver recipientsPrimary EBV infectionPediatric transplant recipientsEpstein-Barr virusEBV nuclear antigenB-cell lymphomaLiver recipientsPediatric EBVCyclosporine monitoringEBV DNAClinical typesPediatric casesSecond syndromeVirus infectionCell lymphomaAdditional casesGreater riskInfectionNuclear antigen
1982
Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody
Miller G, Heston L, Hoffman G. Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody. Infection And Immunity 1982, 37: 1028-1031. PMID: 6182100, PMCID: PMC347642, DOI: 10.1128/iai.37.3.1028-1031.1982.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusMurine monoclonal antibodiesMonoclonal antibodiesCases of mononucleosisB95-8 strainBurkitt's lymphoma cell linesPolyclonal lymphomaBlood transfusionEBV strainsAmerican patientsChallenge virusLymphoma cell linesBurkitt's lymphomaLymphocyte immortalizationAfrican childrenHybridoma antibodiesAntigenic differencesAntibodiesMarmoset cellsMononucleosisVirusAntigenic sitesCell linesLymphomaAntigen
1981
Genome of a mononucleosis epstein-barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates
Fischer D, Miller G, Gradoville L, Heston L, Weststrate M, Maris W, Wright J, Brandsma J, Summers W. Genome of a mononucleosis epstein-barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates. Cell 1981, 24: 543-553. PMID: 6263500, DOI: 10.1016/0092-8674(81)90345-7.Peer-Reviewed Original ResearchMeSH KeywordsBurkitt LymphomaDNA Restriction EnzymesDNA, ViralGenes, ViralHerpesvirus 4, HumanInfectious MononucleosisSalivaSpecies SpecificityConceptsBurkitt's lymphomaB95-8Infectious mononucleosisUncomplicated infectious mononucleosisEpstein-Barr virusSalivary isolatesEBV infectionDisease manifestationsLymphomaMononucleosisPatientsEBVRestriction enzyme analysisVirusMajor insertionC fragmentEnzyme analysisHr-1IsolatesInfectionDeletionAvailable virus
1980
Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus
Robinson J, Brown N, Andiman W, Halliday K, Francke U, Robert M, Andersson-Anvret M, Horstmann D, Miller G. Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus. New England Journal Of Medicine 1980, 302: 1293-1297. PMID: 6245364, DOI: 10.1056/nejm198006053022306.Peer-Reviewed Original Research
1979
SITE OF EPSTEIN-BARR VIRUS REPLICATION IN THE OROPHARYNX
Morgan DG, Miller G, Niederman J, Smith HW, Dowaliby JM. SITE OF EPSTEIN-BARR VIRUS REPLICATION IN THE OROPHARYNX. The Lancet 1979, 314: 1154-1157. PMID: 91888, DOI: 10.1016/s0140-6736(79)92384-5.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseChronic DiseaseHerpesvirus 4, HumanHumansInfectious MononucleosisOropharynxPharynxSalivaSalivary GlandsTonsillitisVirus ReplicationConceptsInfectious Epstein-Barr virusEpstein-Barr virus replicationAcute infectious mononucleosisEpstein-Barr virusInfectious mononucleosisPatient's virusThroat washingsViral antigensEBV productionTonsillar lymphocytesInfectious virusVirus replicationParotid secretionPatientsCell-free formSalivary glandsOropharynxVirusSecretionCell-free materialSalivaMononucleosisCellsTonsillectomyLymphocytesCross-neutralization of infectious mononucleosis and Burkitt lymphoma strains of Epstein-Barr virus with hyperimmune rabbit antisera.
Coope D, Heston L, Brandsma J, Miller G. Cross-neutralization of infectious mononucleosis and Burkitt lymphoma strains of Epstein-Barr virus with hyperimmune rabbit antisera. The Journal Of Immunology 1979, 123: 232-8. PMID: 221591, DOI: 10.4049/jimmunol.123.1.232.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusCell linesMarmoset lymphoblastoid cell lineHuman B lymphoid cellsHR-1 strainDiverse biologic propertiesSource of antigenLymphoblastoid T-cell lineCross-absorption testsT cell linesSera of rabbitsB-lymphoid cellsInhibition of inductionVirus producer cellsImmunization of rabbitsInfectious mononucleosisSupernatant culture fluidsEB virusEarly antigenHyperimmune rabbit antiserumAntibody titersInhibition of transformationLymphoblastoid cell linesLymphoid cellsNormal lymphocytes
1976
Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx
Niederman J, Miller G, Pearson H, Pagano J, Dowaliby J. Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx. New England Journal Of Medicine 1976, 294: 1355-1359. PMID: 177872, DOI: 10.1056/nejm197606172942501.Peer-Reviewed Original ResearchConceptsThroat washingsDuct orificeEpstein-Barr virusDemonstration of virusOropharyngeal sitesInfectious mononucleosisOropharyngeal specimensThird monthIntermittent excretionExcretion patternsAge groupsSecond weekVirusPatientsMonthsOral secretionsSalivaMononucleosisOropharynxExcretionSwabsSecretionWeeks
1975
Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection and interference.
Miller G, Robinson J, Heston L, Lipman M. Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection and interference. IARC Scientific Publications 1975, 395-408. PMID: 190145.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusEarly antigenH virusInitiation of immortalizationAntibody-negative human serumPretreatment of lymphocytesNon-producer cell linesCell linesHuman umbilical cordHuman serumInfectious mononucleosisCarrier cell linesB95-8Umbilical cordBurkitt's lymphomaLymphocyte immortalizationDNA synthesisLaboratory strainsStimulation of DNAHuman lymphocytesLymphocytesBiological behaviorPrimary culturesAbortive infectionAntigen
1974
Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference
Miller G, Robinson J, Heston L, Lipman M. Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference. Proceedings Of The National Academy Of Sciences Of The United States Of America 1974, 71: 4006-4010. PMID: 4372601, PMCID: PMC434316, DOI: 10.1073/pnas.71.10.4006.Peer-Reviewed Original ResearchConceptsEB virusEarly antigenH virusInitiation of immortalizationAntibody-negative human serumEpstein-Barr virusPretreatment of lymphocytesCell linesHuman umbilical cordDNA synthesisHuman serumInfectious mononucleosisCarrier cell linesBiologic behaviorB95-8Umbilical cordBurkitt's lymphomaLymphocyte immortalizationNonproducer cell linesHuman lymphocytesLaboratory strainsLymphocytesBiologic activityPrimary culturesAbortive infection
1973
Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis
Miller G, Niederman J, Andrews L. Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis. New England Journal Of Medicine 1973, 288: 229-232. PMID: 4345064, DOI: 10.1056/nejm197302012880503.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusThroat washesInfectious mononucleosisEpstein-Barr viral antigensEpstein-Barr virus antibodiesInfectious mononucleosis syndromeUmbilical cord leukocytesOropharyngeal excretionClinical symptomsControl subjectsSerum antibodiesVirus antibodiesViral antigensBlood leukocytesSuch antigensComplement fixationContinuous cell linesFactor presentMononucleosisAntibodiesReference seraPatientsCell linesSyndromeLeukocytesRelease of Infectious Epstein-Barr Virus by Transformed Marmoset Leukocytes
Miller G, Lipman M. Release of Infectious Epstein-Barr Virus by Transformed Marmoset Leukocytes. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 190-194. PMID: 4346033, PMCID: PMC433213, DOI: 10.1073/pnas.70.1.190.Peer-Reviewed Original Research
1972
Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood
Miller G, Shope T, Heston L, O'Brien R, Schwartz A, Pearson H. Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood. The Journal Of Pediatrics 1972, 80: 932-937. PMID: 4337277, DOI: 10.1016/s0022-3476(72)80004-0.Peer-Reviewed Original ResearchConceptsEBV antibodiesProspective studyLymphoblastoid cell linesAcutelymphoblastic leukemiaEpstein-Barr virus infectionAntibody-positive childrenAntibody-negative patientsEBV antibody titersAcute lymphoblastic leukemiaCourse of leukemiaCell linesEBV infectionInfectious mononucleosisUntreated patientsMaternal antibodiesCongenital leukemiaSerologic evidenceAntibody titersLymphoblastic leukemiaVirus infectionPatientsLeukemiaProgressive declineEBVUndetectable levels