2022
Systematic review of studies using platelet serotonin content to assess bioeffect of serotonin reuptake inhibitors at the serotonin transporter
Anderson G, Bruno-Pacella I. Systematic review of studies using platelet serotonin content to assess bioeffect of serotonin reuptake inhibitors at the serotonin transporter. Psychopharmacology 2022, 240: 1-13. PMID: 36399187, DOI: 10.1007/s00213-022-06276-5.Peer-Reviewed Original ResearchConceptsSerotonin reuptake inhibitorsSerotonin transporterPlatelet serotonin transporterSERT occupancyReuptake inhibitorsSystematic reviewClinical implicationsPlatelet serotonin contentMeasurement of plateletPlatelet serotonin uptakePractical clinical implicationsStudy of plateletsSerotonin uptakeHealthy controlsSerotonin contentDifferent SSRIsClinical practicePlateletsInhibitorsUptakeSNRIsSSRIsPatientsReviewTransporters
1998
Peripheral serotonin measures in prepubertal psychiatric inpatients and normal children: associations with suicidal behavior and its risk factors
Pfeffer C, McBride P, Anderson G, Kakuma T, Fensterheim L, Khait V. Peripheral serotonin measures in prepubertal psychiatric inpatients and normal children: associations with suicidal behavior and its risk factors. Biological Psychiatry 1998, 44: 568-577. PMID: 9787881, DOI: 10.1016/s0006-3223(98)00020-1.Peer-Reviewed Original ResearchConceptsPrepubertal psychiatric inpatientsBlood tryptophanRisk factorsSerotonin contentSuicidal behaviorMood disordersNormal controlsInpatient childrenSuicidal ideationSerotonin-amplified platelet aggregationPsychiatric inpatientsSuicide attemptsPlatelet serotonin contentEthnic differencesRecent suicide attemptSerotonin measuresPrepubertal controlsPlatelet serotoninPrepubertal childrenInpatientsPlatelet aggregationNormal childrenWhole bloodChildrenDisorders
1992
Platelet and whole blood serotonin content in depressed inpatients: Correlations with acute and life-time psychopathology
Mann J, McBride P, Anderson G, Mieczkowski T. Platelet and whole blood serotonin content in depressed inpatients: Correlations with acute and life-time psychopathology. Biological Psychiatry 1992, 32: 243-257. PMID: 1420642, DOI: 10.1016/0006-3223(92)90106-a.Peer-Reviewed Original ResearchConceptsPlatelet serotonin contentBorderline personality disorderBlood serotonin contentSerotonin contentWhole blood serotonin contentSerotonin levelsHealthy controlsPersonality disorderLower platelet serotonin contentComorbid borderline personality disorderHigher serotonin levelsLow serotonin levelsSeverity of depressionPlatelet serotonin levelsLife-time historyBPD attemptersPatient groupMajor depressionPatientsDepressed inpatientsSuicide attemptsSuicidal behaviorNonborderline patientsWhole bloodDisorders