1982
Assessment of Brain Function in Clinical Pediatric Research: Behavioral and Biological Strategies
Young J, Cohen D, Shaywitz S, Caparulo B, Kavanagh M, Hunt R, Leckman J, Anderson G, Detlor J, Harcherik D, Shaywitz B. Assessment of Brain Function in Clinical Pediatric Research: Behavioral and Biological Strategies. Schizophrenia Bulletin 1982, 8: 205-235. PMID: 6180470, DOI: 10.1093/schbul/8.2.205.Peer-Reviewed Original ResearchConceptsBrain functionPharmacological challenge testsSerious neuropsychiatric disorderClinical pediatric researchClinical research methodsSpecific neuronal systemsAttention deficit disorderClinical syndromeMetabolic dysfunctionTourette syndromeChallenge testClinical protocolsNew treatmentsClinical disordersNeuropsychiatric disordersNeuronal systemsClinical researchPediatric researchSyndromeDeficit disorderBest treatmentDisordersNovel biological strategiesLanguage disordersChildren
1981
Effects of bromocriptine in developing rat pups after 6-hydroxydopamine
Shaywitz B, Lipton S, Teicher M, Cohen D, Anderson G, Batter D, Young J. Effects of bromocriptine in developing rat pups after 6-hydroxydopamine. Pharmacology Biochemistry And Behavior 1981, 15: 443-448. PMID: 6794039, DOI: 10.1016/0091-3057(81)90275-6.Peer-Reviewed Original ResearchConceptsVehicle pupsHigh dosesDays of ageRat pupsCombination of desmethylimipramineInhibitory dopaminergic mechanismDoses of bromocriptineEffects of bromocriptineLittle clinical utilityGeneral motor activityAttention deficit disorderHole boxVehicle animalsDenervation supersensitivityDopaminergic mechanismsBrain dopamineClinical syndromeCommon disorderBromocriptineClinical utilityLonger observation periodPharmacological agentsPostnatal lifeMotor activityFirst month