Gary Kopf, MD
Professor of Surgery (Cardiac)Cards
Contact Info
Cardiac Surgery
PO Box 208062
New Haven, CT 06520-8062
United States
About
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Titles
Professor of Surgery (Cardiac)
Biography
In Memoriam
1945-2026
Dr. Gary Kopf was a board-certified cardiothoracic surgeon. He devoted more than four decades to the care of patients with congenital and acquired heart disease.
Dr. Kopf graduated from Columbia College majoring in Physics. He received his medical degree from Harvard University (cum laude). He trained in General Surgery and Cardiothoracic Surgery at the Brigham and Women’s Hospital, and the Children’s Hospital of Boston. Dr. Kopf spent two years at the National Institutes of Health doing research on perinatal physiology.
Dr. Kopf was a member of the American Association of Thoracic Surgery, The Society of Thoracic Surgery, the American College of Surgeons, and the Congenital Heart Surgeons Society, among many other organizations. He was listed as one of America’s Top Doctors, New York’s Best Doctors, and America’s Top Surgeons for many consecutive years.
Dr. Kopf was also interested in biomedical ethics and is a member of the Adult and Pediatric Ethics Committees at Yale-New Haven Hospital, the Technology and Ethics Working Group, and the End of Life Issues Study Group at the Yale Bioethics Center.
He earned Healthcare Ethics Consultant Certification through the American Society for Bioethics and Humanities, becoming among the first in the health system to receive the HEC-C credential.
Departments & Organizations
- Adult Congenital Heart Program
- Fetal Care Center
- Palliative and End-of-Life Care Education
- Pediatric Cardiovascular Surgery
- Pediatric Cardiovascular Surgery
- Surgery
- Yale Ventures
Education & Training
- Resident
- Peter Bent Brigham Hospital and Children's Hospital, Boston, MA (1980)
- Resident
- Peter Bent Brigham Hospital, Boston, MA (1977)
- Intern
- Roosevelt Hospital, New York, New York (1971)
- MD
- Harvard University (1970)
Research
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Overview
Medical Research Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
George Lister, MD
John Elefteriades, MD
Andrea Amabile, MD
George Tellides, MD, PhD
Madonna Lee, MD, FACS
Peter J. Gruber, MD, PhD
Publications
2024
Extremely Long-Term Follow-Up of Dr William Glenn's Original Patient Cohort With Superior Cavopulmonary Anastomosis (1958-1990)
Lee M, Amabile A, Geirsson A, Gruber P, Kopf G. Extremely Long-Term Follow-Up of Dr William Glenn's Original Patient Cohort With Superior Cavopulmonary Anastomosis (1958-1990). World Journal For Pediatric And Congenital Heart Surgery 2024, 15: 298-302. PMID: 38263670, DOI: 10.1177/21501351231224342.Peer-Reviewed Original ResearchCitationsConceptsSuperior cavopulmonary anastomosisFollow-upGlenn operationCavopulmonary anastomosisRetrospective evaluation of patientsLost to follow-upAdult congenital patientsTetralogy of FallotYears of follow-upOriginal patient cohortEvaluation of patientsGroup of patientsFollow-up dataGlenn patientsCongenital patientsPalliative procedureSurviving patientsPediatric patientsAge of survivorsPatient cohortRetrospective evaluationSurvival ratePatientsMedical recordsElectronic medical records
2003
Novel technique for isolated accessory right heart transplantation for congenital heart disease
Elefteriades J, Lovoulos C, Edwards R, Tittle S, Riley T, Tang P, Rocco E, Kopf G. Novel technique for isolated accessory right heart transplantation for congenital heart disease. Journal Of Thoracic And Cardiovascular Surgery 2003, 125: 1283-1290. PMID: 12830045, DOI: 10.1016/s0022-5223(02)73617-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRight heartSuperior vena cavaRight thoracotomyCardiopulmonary bypassPulmonary arteryDonor heartsVena cavaRight ventricleDonor's superior vena cavaDonor pulmonary arteryDonor right ventricleRight atrial pressureMean arterial pressureCongenital heart diseaseAdult mongrel dogsNovel therapeutic alternativesHeart transplantationPulmonary hypertensionArterial pressureAtrial pressureSuperior venaSinus rhythmAortic valveHeart diseaseLeft atriumRight Coronary Artery Arising from the Left Ventricular Outflow Tract: A Rare Congenital Anomaly of the Coronary Arteries
Moltedo JM, Kopf G, Mello DM, Porter GA. Right Coronary Artery Arising from the Left Ventricular Outflow Tract: A Rare Congenital Anomaly of the Coronary Arteries. Pediatric Cardiology 2003, 24: 598-600. PMID: 14761156, DOI: 10.1007/s00246-002-0384-0.Peer-Reviewed Original Research
2002
Revascularization alone (without mitral valve repair) suffices in patients with advanced ischemic cardiomyopathy and mild-to-moderate mitral regurgitation
Tolis GA, Korkolis DP, Kopf GS, Elefteriades JA. Revascularization alone (without mitral valve repair) suffices in patients with advanced ischemic cardiomyopathy and mild-to-moderate mitral regurgitation. The Annals Of Thoracic Surgery 2002, 74: 1476-1481. PMID: 12440595, DOI: 10.1016/s0003-4975(02)03927-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCongestive heart failureModerate mitral regurgitationMitral regurgitationLong-term survivalEjection fractionIschemic cardiomyopathyHeart failureCongestive heart failure classExcellent long-term survivalPreoperative congestive heart failureImproved left ventricular functionDegree of MRAdvanced ischemic cardiomyopathyHeart failure classCoronary artery bypassMean ejection fractionSevere mitral regurgitationLeft ventricular functionMitral valve operationsNumber of graftsEchocardiographic outcomesHospital mortalitySurgical revascularizationArtery bypassHeart transplantation
1998
Should Angiographically Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo Coronary Artery Bypass Grafting?
Mehta I, Weinberg J, Jones M, Tellides G, Kopf G, Shaw R, Zaret B, Elefteriades J. Should Angiographically Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo Coronary Artery Bypass Grafting? The Annals Of Thoracic Surgery 1998, 65: 17-23. PMID: 9456088, DOI: 10.1016/s0003-4975(97)01192-2.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsSaphenous vein graftsVein graftsRedo CABGDisease-free graftsNR groupRedo Coronary Artery Bypass GraftingR groupCoronary Artery Bypass GraftingRedo coronary artery bypassGood late survivalArtery Bypass GraftingCoronary artery bypassLate myocardial infarctionFirst CABGRecurrent anginaRedo revascularizationArtery bypassBypass GraftingOperative mortalitySurgical mortalityAngiographic evaluationCardiac hospitalizationConsecutive patientsNew stenosisRandomized studyComposite graft with coronary button reimplantation: Procedure of choice for aortic root replacement
Platis I, Kopf G, Dewar M, Shaw R, Elefteriades J. Composite graft with coronary button reimplantation: Procedure of choice for aortic root replacement. International Journal Of Angiology 1998, 41-45. DOI: 10.1055/s-0031-1276089.Peer-Reviewed Original ResearchConceptsAortic root replacementComposite graft replacementProcedure of choiceGraft techniqueButton techniqueRoot replacementBentall techniqueCabrol fistulaGraft replacementAortic rootSaphenous vein graft stenosisCoronary button reimplantationGood early resultsVein graft stenosisSurvival 1 yearAdvanced endocarditisDirect reimplantationHospital mortalitySaphenous graftAcute dissectionAortic replacementPostoperative bleedingCoronary bypassCabrol techniqueGraft stenosis
1987
Biological versus mechanical valves Analysis of 1,116 valves inserted in 1,012 adult patients with a 4,818 patient-year and a 5,327 valve-year follow-up
Hammond G, Geha A, Kopf G, Hashim S. Biological versus mechanical valves Analysis of 1,116 valves inserted in 1,012 adult patients with a 4,818 patient-year and a 5,327 valve-year follow-up. Journal Of Thoracic And Cardiovascular Surgery 1987, 93: 182-198. PMID: 3807394, DOI: 10.1016/s0022-5223(19)36440-2.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBiological valvesMechanical valvesPerivalvular leakValve failureMechanical prosthetic heart valvesYale-New Haven HospitalAnticoagulation-related hemorrhageLate cardiac deathValve-related mortalityValve-related deathIncidence of thromboembolismType of valveYears of ageProsthetic heart valvesAdult patientsTotal morbidityCardiac deathPatientsHeart valvesReoperationThromboembolismSignificant differencesValve analysisLittle direct evidenceYear period
1986
Accessory Mitral Valve Tissue Causing Left Ventricular Outflow Obstruction (Two-Dimensional Echocardiographic Diagnosis and Surgical Approach)
Ascuitto R, Ross-Ascuitto N, Kopf G, Kleinman C, Talner N. Accessory Mitral Valve Tissue Causing Left Ventricular Outflow Obstruction (Two-Dimensional Echocardiographic Diagnosis and Surgical Approach). The Annals Of Thoracic Surgery 1986, 42: 581-584. PMID: 3778009, DOI: 10.1016/s0003-4975(10)60590-5.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsAccessory mitral valve tissueVentricular outflow tract obstructionVentricular outflow obstructionOutflow tract obstructionTwo-dimensional echocardiographyMitral valve tissueNative mitral valveDoppler flow analysisTract obstructionOutflow obstructionPreoperative evaluationRare causeMitral valveIntraoperative techniquesValve tissueAccessory tissuesObstructionTissueEchocardiographySurgeryBupivacaine for Intercostal Nerve Blocks in Children: Blood Concentrations and Pharmacokinetics.
Rothstein P, Arthur G, Feldman H, Kopf G, Covino B. Bupivacaine for Intercostal Nerve Blocks in Children: Blood Concentrations and Pharmacokinetics. Anesthesia & Analgesia 1986, 65: 625. PMID: 3706800, DOI: 10.1213/00000539-198606000-00011.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsIntercostal nerve blockNerve blockBupivacaine concentrationsX minTotal body clearanceVolume of distributionPlasma concentration ratioSteady-state volumeBlood concentration valuesAdult patientsBody clearancePlasma concentrationsBlood concentrationsLocal anestheticsPharmacokinetic evaluationIntercostal spaceBupivacaine HClPharmacokinetic parametersApparent volumeAdditional groupHematocritBupivacaineChildrenClearanceAdultsFate of Left-Sided Cardiac Bioprosthesis Valves in Children
Kopf G, Geha A, Hellenbrand W, Kleinman C. Fate of Left-Sided Cardiac Bioprosthesis Valves in Children. JAMA Surgery 1986, 121: 488-490. PMID: 3954594, DOI: 10.1001/archsurg.1986.01400040126021.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsEmergency valve replacementBioprosthetic valvesValve replacementMitral positionBioprosthetic valve failureMassive mitral regurgitationHigh operative mortalityPediatric age groupElective valve replacementYears of agePorcine bioprosthetic valvesLoss of mobilityLeaflet immobilityHospital mortalityOperative mortalityEmergency surgeryHemodynamic deteriorationMitral stenosisSevere calcificationMitral regurgitationBiologic valvesSevere stenosisThromboembolic phenomenaAortic positionMitral valve
Academic Achievements & Community Involvement
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Activities
activity Presentation
01/01/1985 - PresentResearchDetailsNew York, United StatesAbstract/SynopsisSuperior vena cava-right pulmonary artery anastomosis (SVC-RPA): A long-term follow-up, Second World Congress of Pediatric Cardiology
activity Presentation
01/01/1985 - PresentResearchDetailsNew York, United StatesAbstract/SynopsisSurgical treatment of coarctation complex in neonates: Results and follow-up, Second World Congress of Pediatric Cardiology
Honors
honor The Best Doctors in America: Northeast Region
01/01/2000, 01/01/1996Regional AwardDetailsUnited Stateshonor Peace Medal-International Physicians for Prevention of Nuclear War, St. Petersburg, Russia
01/01/1995International AwardDetailsUnited Stateshonor Paul Harris Fellow-Rotary Foundation of Rotary International
01/01/1995International AwardDetailsUnited Stateshonor Clinical Fellowship Award
01/01/1977UnknownAmerican Cancer SocietyDetailsUnited Stateshonor Honors for Senior Thesis
01/01/1970UnknownHarvard Medical School, Boston, MassachusettsDetailsUnited States
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Cardiac Surgery
PO Box 208062
New Haven, CT 06520-8062
United States