1995
A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder
McDougle C, Kresch L, Goodman W, Naylor S, Volkmar F, Cohen D, Price L. A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder. American Journal Of Psychiatry 1995, 152: 772-777. PMID: 7726318, DOI: 10.1176/ajp.152.5.772.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderRepetitive thoughtsAutistic disorderAutistic groupSex-matched adultsSymptom ChecklistObsessive-compulsive groupDirect discriminant function analysisYale-Brown Obsessive Compulsive Scale Symptom ChecklistYale-Brown Obsessive Compulsive ScaleObsessive-compulsive symptomsCompulsive Scale Symptom ChecklistObsessive Compulsive ScaleAutistic patientsCase-control studyNeurobiological underpinningsSelf-mutilating behaviorCompulsive ScaleDiscriminant function analysisSomatic contentCounting behaviorConsecutive patientsPrimary diagnosisDisorders ClinicTreatment response
1994
Noradrenergic and adrenergic functioning in autism
Minderaa R, Anderson G, Volkmar F, Akkerhuis G, Cohen D. Noradrenergic and adrenergic functioning in autism. Biological Psychiatry 1994, 36: 237-241. PMID: 7986888, DOI: 10.1016/0006-3223(94)90605-x.Peer-Reviewed Original ResearchConceptsUrinary excretion rateNeurochemical assessmentVanillylmandelic acidAdrenergic functioningExcretion rateNormal control individualsUrinary excretionPlasma levelsNoradrenergic functioningMarked abnormalitiesNormal controlsGroup mean differencesControl groupControl individualsNorepinephrineMean differenceAutistic patients