2017
Biochemical risk markers and 10-year incidence of atherosclerotic cardiovascular disease: independent predictors, improvement in pooled cohort equation, and risk reclassification
Akintoye E, Briasoulis A, Afonso L. Biochemical risk markers and 10-year incidence of atherosclerotic cardiovascular disease: independent predictors, improvement in pooled cohort equation, and risk reclassification. American Heart Journal 2017, 193: 95-103. PMID: 29129262, DOI: 10.1016/j.ahj.2017.08.002.Peer-Reviewed Original ResearchConceptsPooled Cohort EquationsNet reclassification indexBiochemical risk markersBiomarker scoreCohort EquationsC-statisticRisk markersTreatment decisionsPrimary atherosclerotic cardiovascular disease (ASCVD) preventionAtherosclerotic cardiovascular disease preventionCategorical net reclassification indexSensitivity C-reactive proteinCategory-free net reclassification indexN-terminal prohormoneBrain natriuretic peptideAtherosclerotic cardiovascular diseaseC-reactive proteinCardiovascular disease preventionMulti-Ethnic StudyRate of incidentsASCVD preventionIndependent predictorsNet reclassificationNatriuretic peptideRisk reclassification
2015
Association between fine particulate matter exposure and subclinical atherosclerosis: A meta-analysis
Akintoye E, Shi L, Obaitan I, Olusunmade M, Wang Y, Newman J, Dodson J. Association between fine particulate matter exposure and subclinical atherosclerosis: A meta-analysis. European Journal Of Preventive Cardiology 2015, 23: 602-612. PMID: 26025448, PMCID: PMC5133694, DOI: 10.1177/2047487315588758.Peer-Reviewed Original ResearchConceptsCarotid intima-media thicknessAnkle-brachial indexIntima-media thicknessSubclinical atherosclerosisArterial calcificationMedia thicknessFine particulate matter exposureAvailable observational studiesParticulate matter exposureRandom-effects modelNumber of studiesObservational studyInclusion criteriaEpidemiological studiesMatter exposureStudy heterogeneityPM2.5 exposureNoninvasive measureAtherosclerosisSimilar associationComprehensive searchConfidence intervalsStatistical significanceCalcificationAssociation