2018
T62. Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control study
Osman G, Rahangdale R, Britton J, Gilmore E, Haider H, Hantus S, Herlopian A, Hocker S, Lee J, Legros B, Punia V, Rampal N, Szaflarski J, Wallace A, Westover M, Hirsch L, Gaspard N. T62. Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control study. Clinical Neurophysiology 2018, 129: e25-e26. DOI: 10.1016/j.clinph.2018.04.063.Peer-Reviewed Original ResearchBilateral independent periodic dischargesCase-control studyRetrospective case-control studyElectrographic seizuresBrain injuryPeriodic dischargesPoor outcomePD groupHospital mortality rateAcute brain injuryAnoxic brain injuryCNS infectionsFrequent etiologyLPD groupHemorrhagic strokeClinical correlatesWorse outcomesLevel of alertnessHigh riskBetter outcomesMortality rateControl groupMultivariate analysisSeizuresEEG patterns
2015
Clinical Correlates and Prognostic Significance of Lateralized Periodic Discharges in Patients Without Acute or Progressive Brain Injury
Sainju RK, Manganas LN, Gilmore EJ, Petroff OA, Rampal N, Hirsch LJ, Gaspard N. Clinical Correlates and Prognostic Significance of Lateralized Periodic Discharges in Patients Without Acute or Progressive Brain Injury. Journal Of Clinical Neurophysiology 2015, 32: 495-500. PMID: 26200591, DOI: 10.1097/wnp.0000000000000206.Peer-Reviewed Original ResearchConceptsProgressive brain injuryAcute brain injuryBrain injuryAbnormal consciousnessPeriodic dischargesClinical correlatesFunctional declineLateralized periodic dischargesRemote brain injuryOutcomes of patientsCase-control studyContinuous EEG monitoringHistory of epilepsyRadiologic evidenceHospital dischargeStatus epilepticusWorse prognosisAcute injuryPrognostic significanceWorse outcomesEEG monitoringMultivariate analysisInjuryPatientsLower likelihood