2018
F80. Seizures and hyperexcitable EEG patterns in spontaneous deep intraparenchymal hemorrhage
Sheikh Z, Stretz C, Maciel C, Dhakar M, Hirsch L, Gilmore E. F80. Seizures and hyperexcitable EEG patterns in spontaneous deep intraparenchymal hemorrhage. Clinical Neurophysiology 2018, 129: e96-e97. DOI: 10.1016/j.clinph.2018.04.243.Peer-Reviewed Original ResearchDeep intraparenchymal hemorrhageAnti-seizure drugsDecompressive hemicraniectomyIntraparenchymal hemorrhageThalamic involvementHematoma volumeContinuous EEGClinical seizuresSedative infusionsSurgical interventionInsular involvementPrior historyHigh riskMean hematoma volumeIncidence of seizuresRisk of seizuresRhythmic delta activitySpike-wave dischargesHigher hematoma volumeRetrospective reviewElectrographic seizuresSubdural hemorrhageHead CTHigh incidencePatients
2015
Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring
Gilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring. Intensive Care Medicine 2015, 41: 686-694. PMID: 25763756, DOI: 10.1007/s00134-015-3709-1.Peer-Reviewed Original ResearchConceptsNonconvulsive seizuresSevere sepsisEEG reactivityPeriodic dischargesLate seizuresSOFA scoreAPACHE IIFunctional outcomeContinuous sedationHigh riskLower riskMedical intensive care unitLong-term cognitive outcomesPresence of sedationAPACHE II scoreGood functional outcomeNonconvulsive status epilepticusIntensive care unitContinuous EEG monitoringAcute brain failureAcademic medical centerNew epilepsyII scoreClinical seizuresMedical ICU