2012
Fetal growth and later maternal death, cardiovascular disease and diabetes
LYKKE JA, PAIDAS MJ, TRICHE EW, LANGHOFF‐ROOS J. Fetal growth and later maternal death, cardiovascular disease and diabetes. Acta Obstetricia Et Gynecologica Scandinavica 2012, 91: 503-510. PMID: 22372730, DOI: 10.1111/j.1600-0412.2011.01355.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBirth WeightCardiovascular DiseasesCohort StudiesDenmarkDiabetes MellitusFemaleFetal DevelopmentFollow-Up StudiesHealth Status IndicatorsHumansInfant, NewbornMiddle AgedMortality, PrematurePregnancyProportional Hazards ModelsReference StandardsRegistriesRetrospective StudiesRiskYoung AdultConceptsSubsequent maternal deathIschemic heart diseaseFetal growthPonderal indexMaternal deathsStandardized birthweightHeart diseaseCardiovascular diseaseSubsequent mortalityCox proportional hazards modelFirst singleton deliverySmaller risk estimatesSubsequent diabetes mellitusRetrospective cohort studyProportional hazards modelCardiovascular morbidityPregnancy complicationsCohort studySingleton deliveriesDiabetes mellitusGestational ageLow birthweightPrimary exposureSubsequent riskEarly deathFetal growth and later maternal death, cardiovascular disease and diabetes
LYKKE J, PAIDAS M, TRICHE E, LANGHOFF‐ROOS J. Fetal growth and later maternal death, cardiovascular disease and diabetes. Acta Obstetricia Et Gynecologica Scandinavica 2012, no-no. DOI: 10.1111/j.1600-0412.2012.01355.x.Peer-Reviewed Original ResearchSubsequent maternal deathIschemic heart diseaseFetal growthPonderal indexMaternal deathsStandardized birthweightHeart diseaseCardiovascular diseaseSubsequent mortalityFirst singleton deliverySmaller risk estimatesSubsequent diabetes mellitusProportional hazards modelCardiovascular morbidityPregnancy complicationsSingleton deliveriesDiabetes mellitusGestational ageLow birthweightPrimary exposureSubsequent riskEarly deathHazards modelBirthweightPremature death
2011
Preimplantation factor (PIF) analog prevents type I diabetes mellitus (TIDM) development by preserving pancreatic function in NOD mice
Weiss L, Bernstein S, Jones R, Amunugama R, Krizman D, JeBailey L, Hazan O, Yachtin J, Shiner R, Reibstein I, Triche E, Slavin S, Or R, Barnea E. Preimplantation factor (PIF) analog prevents type I diabetes mellitus (TIDM) development by preserving pancreatic function in NOD mice. Endocrine 2011, 40: 41. PMID: 21424847, DOI: 10.1007/s12020-011-9438-5.Peer-Reviewed Original ResearchConceptsIntraperitoneal glucose tolerance testInsulin stainingPreImplantation FactorPancreatic functionPreventive effectNormal intraperitoneal glucose tolerance testsIslet architectureType 1 diabetes mellitusPancreatic islet insulinOnset of diabetesGlucose tolerance testExocrine pancreatic functionDiabetic murine modelInsulin receptor expressionPathway analysisSPIF effectNOD miceDiabetes mellitusSignal pathway analysisNeutrophil invasionTh1 cytokinesDiabetes developmentMellitus developmentContinuous administrationMaternal immunity
2009
Hypertensive Pregnancy Disorders and Subsequent Cardiovascular Morbidity and Type 2 Diabetes Mellitus in the Mother
Lykke JA, Langhoff-Roos J, Sibai BM, Funai EF, Triche EW, Paidas MJ. Hypertensive Pregnancy Disorders and Subsequent Cardiovascular Morbidity and Type 2 Diabetes Mellitus in the Mother. Hypertension 2009, 53: 944-951. PMID: 19433776, DOI: 10.1161/hypertensionaha.109.130765.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiovascular DiseasesCase-Control StudiesCohort StudiesDenmarkDiabetes Mellitus, Type 2FemaleHumansHypertension, Pregnancy-InducedIncidencePre-EclampsiaPregnancyPregnancy OutcomePregnancy RatePregnancy, High-RiskPremature BirthProbabilityProportional Hazards ModelsRegistriesSeverity of Illness IndexYoung AdultConceptsType 2 diabetes mellitusSubsequent type 2 diabetes mellitusHypertensive pregnancy disordersSubsequent cardiovascular eventsDiabetes mellitusGestational hypertensionSevere preeclampsiaPregnancy disordersSubsequent hypertensionCardiovascular eventsRegistry-based cohort studyConsecutive singleton deliveriesSubsequent cardiovascular morbidityCongestive heart failureIschemic heart diseaseCardiovascular morbidityPlacental abruptionPreterm deliveryThromboembolic eventsCohort studyMild preeclampsiaSingleton deliveriesHeart failureSubsequent thromboembolismGestational age
2008
204: Small and large for gestational age birthweight in offspring are risk factors for subsequent maternal cardiovascular morbidity and type 2 diabetes mellitus
Lykke J, Damm P, Paidas M, Triche E, Sibai B, Langhoff-Roos J. 204: Small and large for gestational age birthweight in offspring are risk factors for subsequent maternal cardiovascular morbidity and type 2 diabetes mellitus. American Journal Of Obstetrics And Gynecology 2008, 199: s68. DOI: 10.1016/j.ajog.2008.09.231.Peer-Reviewed Original Research