Elias Lolis, PhD

Elias Lolis was trained in structural biology earning his PhD in Chemistry from MIT and, as a postdoctoral associate at the Laboratory of Medical Biochemistry at Rockefeller University studying the functional interaction between advanced glycation end products (AGEs) and the immune system. He currently studies chemokines, macrophage migration inhibitory factor (MIF family of proteins), and their receptors in disease (cancer, inflammation, and infection) using techniques ranging from structural biology, Crispr/Cas9 gene editing in mouse models of disease, and high throughput screening of small molecules and biotherapeutics. He has national and international collaborations on phosphatases, proteins of SARS-CoV-2, and MIF. He received a Pharmaceutical Manufacturers Association Faculty Development Award in Basic Pharmacology, the Donaghue Young Investigator Award, and the GlaxoWellcome Award in Drug Discovery. He is the founder and co-founder of the Macromolecular X-ray Core Facility and Yale Keck Bioinformatics Resource, respectively. He trained 25 PhDs and postdoctoral associates, two postgrads, seven Yale undergraduates, ten under-represented minority summer students (BioStep and PREP), and 22 undergraduates and high school students from various schools. He currently serves as the Faculty Director of the Office of Postdoctoral Affairs for Yale University and the Director of Graduate Studies for the Department of Pharmacology.