2020
Hepatocellular neoplasms arising in genetic metabolic disorders: steatosis is common in both the tumor and background liver
Cheng L, Jain D, Kakar S, Torbenson MS, Wu TT, Yeh MM. Hepatocellular neoplasms arising in genetic metabolic disorders: steatosis is common in both the tumor and background liver. Human Pathology 2020, 108: 93-99. PMID: 33245984, DOI: 10.1016/j.humpath.2020.11.012.Peer-Reviewed Original ResearchConceptsGenetic metabolic disordersMetabolic disordersHepatocellular neoplasmsBackground liverType 1Ornithine carbamyl transferase deficiencyRare genetic metabolic disorderRare case reportBackground liver parenchymaGlycogen storage disease type 1Hereditary tyrosinemia type 1Disease type 1Tyrosinemia type 1Younger patientsRetrospective studyCase reportCommon findingLiver parenchymaSteatosisTransferase deficiencyPathological characterizationNeoplasmsTumorsDisordersPatients
2019
Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas arising from an intraductal papillary mucinous neoplasm
Charifa A, Walther Z, Salem R, Jain D. Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas arising from an intraductal papillary mucinous neoplasm. Human Pathology Reports 2019, 15: 95-98. DOI: 10.1016/j.ehpc.2018.12.007.Peer-Reviewed Case Reports and Technical NotesOsteoclast-like giant cellsUndifferentiated carcinomaInvasive carcinomaGiant cellsMucinous neoplasmsEndoscopic ultrasoundIntraductal papillary mucinous neoplasmIntraductal mucinous neoplasmPapillary mucinous neoplasmRare pancreatic tumorPancreatic ductal carcinomaDuctal lesionsDuctal carcinomaPancreatic tumorsPancreatic adenocarcinomaCarcinoma subtypesHistological examinationPancreatic massCarcinomaEpithelial markersAmpullary massEpithelial originIPMNNeoplastic progressionNeoplasmsKnowledge gaps in the appendix: a multi-institutional study from seven academic centers
Arnold CA, Graham RP, Jain D, Kakar S, Lam-Himlin DM, Naini BV, Wu TT, Yeh MM, Torbenson MS. Knowledge gaps in the appendix: a multi-institutional study from seven academic centers. Modern Pathology 2019, 32: 988-996. PMID: 30765881, DOI: 10.1038/s41379-019-0216-x.Peer-Reviewed Original ResearchConceptsLow-grade appendiceal mucinous neoplasmGrade appendiceal mucinous neoplasmAppendiceal mucinous neoplasmGoblet cell carcinoidMucinous neoplasmsCell carcinoidExtra-appendiceal mucinHigh-risk featuresUnique diagnostic challengeHigh-grade atypiaMulti-institutional studyAppendix pathologyDiverticular diseaseMucinous adenocarcinomaDiagnostic challengeSerrated polypsAcademic centersNeoplasmsCommon knowledge gapsCarcinoidsConsultsAdenocarcinomaAdditional studiesDiagnosisPathologists
2011
Pseudointraductal papillary mucinous neoplasia caused by microscopic periductal endocrine tumors of the pancreas: a report of 3 cases
Kenney B, Singh G, Salem RR, Paterno F, Robert ME, Jain D. Pseudointraductal papillary mucinous neoplasia caused by microscopic periductal endocrine tumors of the pancreas: a report of 3 cases. Human Pathology 2011, 42: 1034-1041. PMID: 21292301, DOI: 10.1016/j.humpath.2010.09.018.Peer-Reviewed Original ResearchConceptsIntraductal papillary mucinous neoplasmPapillary mucinous neoplasmMucinous neoplasmsEndocrine tumorsPancreatic ductEndocrine neoplasmsDistinctive pancreatic tumorsExtensive mucin productionMain pancreatic ductPancreatic endocrine tumorsConstellation of findingsPancreatic endocrine neoplasmsDuct stricturesMucinous neoplasiaCystic lesionsPancreatic tumorsMucin productionNeoplasmsPapillary epitheliumTumorsDuctSuch casesConvincing featuresResectionStricture