2020
Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients
Gaston DC, Malinis M, Osborn R, Peaper DR, Landry M, Juthani-Mehta M, Azar MM. Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients. American Journal Of Transplantation 2020, 21: 1304-1311. PMID: 33043603, PMCID: PMC7675520, DOI: 10.1111/ajt.16357.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsOrgan transplant recipientsClinical implicationsCycle threshold valuesSOT patientsTransplant recipientsSymptom onsetYale New Haven Health SystemUpper respiratory tract samplesSARS-CoV-2 viral RNASARS-CoV-2 viral dynamicsAdult SOT recipientsRetrospective chart reviewRespiratory tract samplesSARS-CoV-2 cycle threshold valuesInfection prevention measuresCOVID-19 severityViral RNAHigher clinical acuityPrimary diagnostic testRT-PCR assaysSOT recipientsChart reviewViral loadAdmission severity
2016
Clinical Utility of On-Demand Multiplex Respiratory Pathogen Testing among Adult Outpatients
Green DA, Hitoaliaj L, Kotansky B, Campbell SM, Peaper DR. Clinical Utility of On-Demand Multiplex Respiratory Pathogen Testing among Adult Outpatients. Journal Of Clinical Microbiology 2016, 54: 2950-2955. PMID: 27654334, PMCID: PMC5121384, DOI: 10.1128/jcm.01579-16.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAmbulatory Care FacilitiesAnti-Bacterial AgentsAsthmaEmergency Service, HospitalFemaleHumansInfluenza, HumanMaleMiddle AgedOrthomyxoviridaeOseltamivirPractice Patterns, Physicians'Pulmonary Disease, Chronic ObstructiveRespiratory Tract InfectionsRetrospective StudiesConceptsNon-influenza virusesRespiratory pathogen testingInfluenza virusAntibiotic prescriptionsPrescription ratesAdult outpatientsLarge Veterans Administration Medical CenterVeterans Administration Medical CenterAntibiotic prescription ratesPathogen testingRespiratory tract infectionsUnnecessary antibiotic useFilmArray Respiratory PanelPatients' medical recordsSpecific therapeutic interventionsTract infectionsRespiratory panelOutpatient centerAntibiotic useAntimicrobial prescriptionsMedical recordsRespiratory pathogensMedical CenterClinical utilityCommon pathogens