2019
Movement and Performance Explain Widespread Cortical Activity in a Visual Detection Task
Salkoff D, Zagha E, McCarthy E, McCormick D. Movement and Performance Explain Widespread Cortical Activity in a Visual Detection Task. Cerebral Cortex 2019, 30: 421-437. PMID: 31711133, PMCID: PMC7029483, DOI: 10.1093/cercor/bhz206.Peer-Reviewed Original ResearchConceptsVisual detection taskSecondary motor cortexTask performanceTask-related movementsCortical activityMotor cortexDetection taskTask-independent processesOptimal task performanceWidespread cortical activityTask-related changesHead-fixed miceResponse choicesDorsal cortexOrofacial movementsNeural activityTrial variationLick responsesArousal stateTrial variabilityTarget trialsLick rateCortexCortical signalsTrials
2015
Competing Neural Ensembles in Motor Cortex Gate Goal-Directed Motor Output
Zagha E, Ge X, McCormick DA. Competing Neural Ensembles in Motor Cortex Gate Goal-Directed Motor Output. Neuron 2015, 88: 565-577. PMID: 26593093, PMCID: PMC4660255, DOI: 10.1016/j.neuron.2015.09.044.Peer-Reviewed Original ResearchConceptsPopulations of neuronsAnticipation of movementMotor cortexCortical neuronsCortical circuitsIntracellular techniquesUnit recordingsNeural ensemblesMotor outputNeuronsSensory stimuliNeural activityMotor representationsSensory detection taskMotor commandsFuture studiesTask-related neural dynamicsCortexMiceCellular activities
2013
Motor Cortex Feedback Influences Sensory Processing by Modulating Network State
Zagha E, Casale AE, Sachdev RN, McGinley MJ, McCormick DA. Motor Cortex Feedback Influences Sensory Processing by Modulating Network State. Neuron 2013, 79: 567-578. PMID: 23850595, PMCID: PMC3742632, DOI: 10.1016/j.neuron.2013.06.008.Peer-Reviewed Original Research
1985
Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex
McCormick D, Connors B, Lighthall J, Prince D. Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex. Journal Of Neurophysiology 1985, 54: 782-806. PMID: 2999347, DOI: 10.1152/jn.1985.54.4.782.Peer-Reviewed Original ResearchConceptsRegular-spiking cellsAction potentialsSpiny stellate neuronsIntracellular recording techniquesAnterior cingulate areaDistinct neuronal classesAnterior cingulate cortexProminent afterhyperpolarizationTonic currentsStellate neuronsMean durationTrain of spikesCingulate areasFluorescent dye Lucifer Yellow CHDye Lucifer Yellow CHSynaptic pathwaysIntracellular injectionSpike frequencyCingulate cortexFast spikingSpike riseElectrophysiological propertiesNeuronal classesGuinea pigsComparative electrophysiology