2011
Active Action Potential Propagation But Not Initiation in Thalamic Interneuron Dendrites
Casale A, McCormick D. Active Action Potential Propagation But Not Initiation in Thalamic Interneuron Dendrites. Journal Of Neuroscience 2011, 31: 18289-18302. PMID: 22171033, PMCID: PMC3269759, DOI: 10.1523/jneurosci.4417-11.2011.Peer-Reviewed Original ResearchConceptsDorsal lateral geniculate nucleusLateral geniculate nucleusSomatic current injectionAction potentialsDendritic arborsGeniculate nucleusSynaptic stimulationThalamic interneuronsMouse dorsal lateral geniculate nucleusDendritic neurotransmitter releaseEntire dendritic arborSingle action potentialAxon initial segmentVoltage-gated sodiumProximal dendritesDendritic appendagesInhibitory neurotransmitterExcitatory inputsInhibitory interneuronsVoltage-sensitive dyeSynaptic inputsThalamocortical cellsCalcium transientsCalcium imagingNeurotransmitter release
1989
GABA as an inhibitory neurotransmitter in human cerebral cortex
McCormick D. GABA as an inhibitory neurotransmitter in human cerebral cortex. Journal Of Neurophysiology 1989, 62: 1018-1027. PMID: 2573696, DOI: 10.1152/jn.1989.62.5.1018.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsGamma-aminobutyric acidEarly inhibitory postsynaptic potentialHuman cerebral cortexExcitatory postsynaptic potentialsAverage reversal potentialCerebral cortexInhibitory neurotransmitterPostsynaptic potentialsLate inhibitory postsynaptic potentialsSlow inhibitory postsynaptic potentialGABAergic inhibitory postsynaptic potentialsInitial excitatory postsynaptic potentialsReversal potentialGABAB agonist baclofenGABAB antagonist phaclofenGABAA antagonist bicucullineGABAA agonist muscimolParoxysmal epileptiform activityMajor inhibitory neurotransmitterVitro. 2Antagonist phaclofenMembrane conductanceAgonist baclofenAntagonist bicuculline