1992
Mesangial cell-matrix interactions. Effects on mesangial cell growth and cytokine secretion.
Ruef C, Kashgarian M, Coleman D. Mesangial cell-matrix interactions. Effects on mesangial cell growth and cytokine secretion. American Journal Of Pathology 1992, 141: 429-39. PMID: 1323220, PMCID: PMC1886618.Peer-Reviewed Original ResearchConceptsIL-6 secretionInterleukin-6Mesangial cellsCytokine secretionMC growthIL-6 releaseIL-1 alphaMesangial cell growthDose-dependent mannerMesangioproliferative GNInflammatory mediatorsInflammatory cellsTNF-alphaCollagen type IVCollagen type ISecretionColl IType IVExtracellular matrix proteinsProliferative phenotypeCytokinesType ICell growthMatrix proteinsCells
1989
Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor.
Horowitz M, Coleman D, Flood P, Kupper T, Jilka R. Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor. Journal Of Clinical Investigation 1989, 83: 149-157. PMID: 2642917, PMCID: PMC303655, DOI: 10.1172/jci113852.Peer-Reviewed Original ResearchConceptsParathyroid hormoneGranulocyte-macrophage colony-stimulating factorColony-stimulating factorOsteoclast activityDose of PTHGM-CSFNumber of osteoclastsSecretion of cytokinesBone active agentsUnknown cytokinesSpecific cytokinesCytokinesCulture resultsPrimary murine osteoblastsActive inductionLipopolysaccharideSecretion of collagenSecretionSerological techniquesNew boneMurine osteoblastsHormone
1988
Hematopoietic, Lymphopoietic, and Proinflammatory Cytokines Produced by Human and Murine Keratinocytes
KUPPER T, HOROWITZ M, BIRCHALL N, MIZUTANI H, COLEMAN D, McGUIRE J, FLOOD P, DOWER S, LEE F. Hematopoietic, Lymphopoietic, and Proinflammatory Cytokines Produced by Human and Murine Keratinocytes. Annals Of The New York Academy Of Sciences 1988, 548: 262-270. PMID: 2470299, DOI: 10.1111/j.1749-6632.1988.tb18814.x.Peer-Reviewed Original Research
1986
Keratinocyte-derived T-cell growth factor: a T-cell growth factor functionally distinct from interleukin 2.
Kupper T, Coleman D, McGuire J, Goldminz D, Horowitz M. Keratinocyte-derived T-cell growth factor: a T-cell growth factor functionally distinct from interleukin 2. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 4451-4455. PMID: 3520573, PMCID: PMC323751, DOI: 10.1073/pnas.83.12.4451.Peer-Reviewed Original ResearchConceptsT cell growth factorIL-2-dependent cell lineT cellsT lymphocytesGrowth factorInterleukin-2Trophic factorsIL-2-dependent cell line HT-2Cell linesCertain dermatologic disordersConventional IL-2IL-2-dependent T cell lineActivated T lymphocytesIL-2 preparationsMicroenvironment of skinT cell linesGel-filtration HPLC analysisDermatologic disordersIL-2CTLL-2 cellsPreferential proliferationLymphocytesEpithelial cellsEpidermal epithelial cellsDifferential effects