1993
PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements
Rupprecht H, Sukhatme V, Lacy J, Sterzel R, Coleman D. PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements. American Journal Of Physiology 1993, 265: f351-f360. PMID: 8214093, DOI: 10.1152/ajprenal.1993.265.3.f351.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceDNA-Binding ProteinsEarly Growth Response Protein 1Gene ExpressionGlomerular MesangiumImmediate-Early ProteinsMolecular Sequence DataNuclear ProteinsOligonucleotide ProbesPhosphorylationPlatelet-Derived Growth FactorPromoter Regions, GeneticRatsSerum Response FactorTranscription FactorsTranscription, GeneticTyrosineConceptsPlatelet-derived growth factorPDGF stimulationElectrophoretic mobility shift assaysNuclear run-off assaysPromoter deletion analysisEgr-1 transcriptionEarly growth response gene-1Serum response elementUpstream serum response elementsProtein tyrosine phosphorylationMobility shift assaysRun-off assaysResponse gene-1Egr-1 inductionEgr-1 mRNAEgr-1 expressionImmediate early genesTranscriptional inductionDeletion analysisTyrosine phosphorylationShift assaysTranscriptional levelConsensus sequenceTranscription rateGene expression
1992
Effect of vasoactive agents on induction of Egr-1 in rat mesangial cells: correlation with mitogenicity
Rupprecht H, Dann P, Sukhatme V, Sterzel R, Coleman D. Effect of vasoactive agents on induction of Egr-1 in rat mesangial cells: correlation with mitogenicity. American Journal Of Physiology 1992, 263: f623-f636. PMID: 1415734, DOI: 10.1152/ajprenal.1992.263.4.f623.Peer-Reviewed Original ResearchMeSH KeywordsAngiotensin IIAnimalsArginine VasopressinDNA-Binding ProteinsEarly Growth Response Protein 1Gene Expression RegulationGlomerular MesangiumImmediate-Early ProteinsMaleMitogensPlatelet-Derived Growth FactorProtein Kinase CRatsRats, Sprague-DawleyRNA, MessengerSerotoninTime FactorsTranscription FactorsVasoconstrictionVasodilation