1997
Glomerular epithelial cell products stimulate mesangial cell proliferation in culture
Budde K, Neumayer H, Salant D, Cybulsky A, Coleman D, Sterzel R. Glomerular epithelial cell products stimulate mesangial cell proliferation in culture. Kidney International 1997, 52: 733-741. PMID: 9291194, DOI: 10.1038/ki.1997.389.Peer-Reviewed Original ResearchConceptsGlomerular epithelial cellsMC growth factorsMesangial cellsGlomerular diseaseGrowth factorMesangial cell proliferationEpithelial cell productsQuiescent rat mesangial cellsRat mesangial cellsIL-6IL-4IL-5TNF-alphaIL-2Glomerular cell typesIL-1GM-CSFTGF betaSoluble factorsProliferative activityCell productsCompetitive binding assaysEpithelial cellsMitogenic activityCell proliferation
1994
Analysis of Egr-1 protein induction in murine peritoneal macrophages treated with granulocyte-macrophage colony-stimulating factor.
Li C, Mitchell D, Coleman D. Analysis of Egr-1 protein induction in murine peritoneal macrophages treated with granulocyte-macrophage colony-stimulating factor. The Yale Journal Of Biology And Medicine 1994, 67: 269-76. PMID: 8579643, PMCID: PMC2588905.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBlotting, WesternCell DivisionDNA-Binding ProteinsDose-Response Relationship, DrugEarly Growth Response Protein 1Granulocyte-Macrophage Colony-Stimulating FactorImmediate-Early ProteinsMacrophages, PeritonealMiceMolecular Sequence DataThioglycolatesTranscription FactorsConceptsEgr-1 proteinMurine peritoneal macrophagesEarly growth response gene-1Macrophage proliferationGranulocyte-macrophage colony-stimulating factorResponse gene-1Egr-1 mRNAProtein speciesColony-stimulating factorGM-CSFPathogen invasionWestern blot analysisGene 1Stimulation of macrophagesMacrophage differentiationPeritoneal macrophagesProtein inductionProteinBlot analysisTranscriptionProliferationGM-CSF inductionInductionMacrophagesPhysiologic circumstances
1989
Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor
Budde K, Coleman D, Lacy J, Sterzel R. Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor. American Journal Of Physiology 1989, 257: f1065-f1078. PMID: 2690641, DOI: 10.1152/ajprenal.1989.257.6.f1065.Peer-Reviewed Original ResearchConceptsRat mesangial cellsGranulocyte-macrophage colony-stimulating factorCultured rat mesangial cellsMesangial cellsColony-stimulating factorGM-CSFMC-CMGlomerular mesangial cellsPeritoneal MPsEffector cellsIL-2Inflammatory processGlomerular diseaseInterleukin-2T cellsT lymphocytesInterleukin-4Murine GM-CSFRenal glomeruliSerum-free conditionsSoluble factorsProliferative activitySpecific cDNA probesGM-CSF mRNA transcriptsPresent findingsParathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor.
Horowitz M, Coleman D, Flood P, Kupper T, Jilka R. Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor. Journal Of Clinical Investigation 1989, 83: 149-157. PMID: 2642917, PMCID: PMC303655, DOI: 10.1172/jci113852.Peer-Reviewed Original ResearchConceptsParathyroid hormoneGranulocyte-macrophage colony-stimulating factorColony-stimulating factorOsteoclast activityDose of PTHGM-CSFNumber of osteoclastsSecretion of cytokinesBone active agentsUnknown cytokinesSpecific cytokinesCytokinesCulture resultsPrimary murine osteoblastsActive inductionLipopolysaccharideSecretion of collagenSecretionSerological techniquesNew boneMurine osteoblastsHormone
1988
Granulocyte-Macrophage Colony-Stimulating Factor Enhances Selective Effector Functions of Tissue-Derived Macrophages
Coleman D, Chodakewitz J, Bartiss A, Mellors J. Granulocyte-Macrophage Colony-Stimulating Factor Enhances Selective Effector Functions of Tissue-Derived Macrophages. Blood 1988, 72: 573-578. DOI: 10.1182/blood.v72.2.573.573.Peer-Reviewed Original ResearchFc-dependent phagocytosisAnti-Toxoplasma activityGM-CSFTissue-derived macrophagesRecombinant GM-CSFClass II major histocompatibility antigensGranulocyte-macrophage colony-stimulating factorMacrophage oxidative metabolismMajor histocompatibility antigensSite of exposureGM-CSF antibodyColony-stimulating factorMurine recombinant GM-CSFThioglycollate-elicited cellsGranulocyte-macrophage colonyPhorbol myristate acetateNeutrophil functionHistocompatibility antigensEffector functionsVariety of cellsFunctional capacityMacrophage functionThioglycollate-elicited macrophagesResident macrophagesPeritoneal macrophagesKeratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
Kupper T, Lee F, Coleman D, Chodakewitz J, Flood P, Horowitz M. Keratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF). Journal Of Investigative Dermatology 1988, 91: 185-188. PMID: 3294304, DOI: 10.1111/1523-1747.ep12464470.Peer-Reviewed Original ResearchConceptsS1 nuclease analysisCell linesMurine T cell lineVariety of biochemicalsGrowth factorMurine GM-CSF cDNAGM-CSFNuclease analysisCultured neonatal keratinocytesGM-CSF cDNARecombinant murine GM-CSFMurine GM-CSFKeratinocyte cell lineT-cell activating propertiesT cell growth factorMacrophage-colony stimulating factorT cell linesGranulocyte macrophage-colony stimulating factorImmunochemical criteriaHigh specific activityProliferationSpecific activityColony-Stimulating FactorHT-2 cellsPam 212Granulocyte-macrophage colony-stimulating factor enhances selective effector functions of tissue-derived macrophages.
Coleman D, Chodakewitz J, Bartiss A, Mellors J. Granulocyte-macrophage colony-stimulating factor enhances selective effector functions of tissue-derived macrophages. Blood 1988, 72: 573-8. PMID: 3042043, DOI: 10.1182/blood.v72.2.573.bloodjournal722573.Peer-Reviewed Original ResearchConceptsFc-dependent phagocytosisAnti-Toxoplasma activityGranulocyte-macrophage colony-stimulating factorGM-CSFColony-stimulating factorTissue-derived macrophagesRecombinant GM-CSFClass II major histocompatibility antigensMacrophage oxidative metabolismMajor histocompatibility antigensSite of exposureGM-CSF antibodyMurine recombinant GM-CSFThioglycollate-elicited cellsPhorbol myristate acetateNeutrophil functionHistocompatibility antigensEffector functionsVariety of cellsFunctional capacityMacrophage functionThioglycollate-elicited macrophagesResident macrophagesPeritoneal macrophagesStimulatory effect