1988
Keratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
Kupper T, Lee F, Coleman D, Chodakewitz J, Flood P, Horowitz M. Keratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF). Journal Of Investigative Dermatology 1988, 91: 185-188. PMID: 3294304, DOI: 10.1111/1523-1747.ep12464470.Peer-Reviewed Original ResearchConceptsS1 nuclease analysisCell linesMurine T cell lineVariety of biochemicalsGrowth factorMurine GM-CSF cDNAGM-CSFNuclease analysisCultured neonatal keratinocytesGM-CSF cDNARecombinant murine GM-CSFMurine GM-CSFKeratinocyte cell lineT-cell activating propertiesT cell growth factorMacrophage-colony stimulating factorT cell linesGranulocyte macrophage-colony stimulating factorImmunochemical criteriaHigh specific activityProliferationSpecific activityColony-Stimulating FactorHT-2 cellsPam 212
1986
Keratinocyte-derived T-cell growth factor: a T-cell growth factor functionally distinct from interleukin 2.
Kupper T, Coleman D, McGuire J, Goldminz D, Horowitz M. Keratinocyte-derived T-cell growth factor: a T-cell growth factor functionally distinct from interleukin 2. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 4451-4455. PMID: 3520573, PMCID: PMC323751, DOI: 10.1073/pnas.83.12.4451.Peer-Reviewed Original ResearchConceptsT cell growth factorIL-2-dependent cell lineT cellsT lymphocytesGrowth factorInterleukin-2Trophic factorsIL-2-dependent cell line HT-2Cell linesCertain dermatologic disordersConventional IL-2IL-2-dependent T cell lineActivated T lymphocytesIL-2 preparationsMicroenvironment of skinT cell linesGel-filtration HPLC analysisDermatologic disordersIL-2CTLL-2 cellsPreferential proliferationLymphocytesEpithelial cellsEpidermal epithelial cellsDifferential effects