Early Biochemical Events in Pneumococcal Otitis Media: Arachidonic Acid Metabolites in Middle Ear Fluid
Nonomura N, Giebink G, Harada T, Zelterman D, Juhn S. Early Biochemical Events in Pneumococcal Otitis Media: Arachidonic Acid Metabolites in Middle Ear Fluid. Annals Of Otology Rhinology & Laryngology 1991, 100: 385-388. PMID: 1850967, DOI: 10.1177/000348949110000507.Peer-Reviewed Original ResearchMeSH Keywords6-Ketoprostaglandin F1 alphaAnimalsArachidonic AcidArachidonic AcidsChinchillaDinoprostoneLeukotriene B4Otitis Media with EffusionPneumococcal InfectionsSRS-ATime FactorsConceptsMiddle ear fluidArachidonic acid metabolitesEar fluidLeukotriene B4Acid metabolitesPneumococcal otitis mediaSubsequent inflammatory responseInflammatory cell chemotaxisStreptococcus pneumoniae organismsMiddle ear inoculationInflammatory cellsOtitis mediaF1 alphaInflammatory responseProstaglandin E2Pneumoniae organismsArachidonate metabolitesArachidonic acidCell chemotaxisEar inoculationEarly biochemical eventsSignificant increaseInitial stimulusHoursMetabolites