2023
Performance and reliability assessment of a lower dose, task-based scoliosis radiography protocol in pediatric patients
Al-Dasuqi K, Taylor E, Ehrlich L, Cooperman D, Socci A, Tuason D, Hoerner M, Staib L, Silva C. Performance and reliability assessment of a lower dose, task-based scoliosis radiography protocol in pediatric patients. Pediatric Radiology 2023, 54: 146-153. PMID: 38010426, DOI: 10.1007/s00247-023-05812-5.Peer-Reviewed Original ResearchConceptsDose area productPatient heightAdequate image qualityEffective doseExposure indexMedian effective doseLower radiation exposureComparison of proportionsChi-squared testIntraclass correlation coefficientBland-Altman plotsConsecutive patientsPediatric patientsIncident air kermaDose reductionLow doseSkeletal maturityRadiographsPatientsAir kermaRadiation exposureScoliosis radiographyStatistical significanceDoseSpinal curvature
2022
Ultrasound for Midgut Malrotation and Midgut Volvulus: AJR Expert Panel Narrative Review.
Nguyen HN, Navarro OM, Bloom DA, Feinstein KA, Guillerman RP, Munden MM, Sammer MBK, Silva CT. Ultrasound for Midgut Malrotation and Midgut Volvulus: AJR Expert Panel Narrative Review. American Journal Of Roentgenology 2022, 218: 931-939. PMID: 35107311, DOI: 10.2214/ajr.21.27242.Peer-Reviewed Original ResearchConceptsMidgut malrotationUse of ultrasoundMidgut volvulusNarrative reviewAJR Expert Panel Narrative ReviewUpper gastrointestinal seriesUse of USPediatric surgical emergencyImaging modalitiesFirst-line modalityPreferred imaging modalityBowel ischemiaGastrointestinal seriesSurgical emergencyMalrotationAccurate diagnosisVolvulusModalitiesDiagnosisUltrasound
2021
The course of the duodenum: what path should we take? Reply to Binu et al.
Nguyen HN, Silva CT, Guillerman RP, Navarro OM, Van Tassel D, Sammer MBK. The course of the duodenum: what path should we take? Reply to Binu et al. Pediatric Radiology 2021, 51: 2101-2101. PMID: 34415359, DOI: 10.1007/s00247-021-05164-y.Peer-Reviewed Original ResearchDuodenumHumansAge-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial.
Faustino EVS, Raffini LJ, Hanson SJ, Cholette JM, Pinto MG, Li S, Kandil SB, Nellis ME, Shabanova V, Silva CT, Tala JA, McPartland T, Spinella PC. Age-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial. Critical Care Medicine 2021, 49: e369-e380. PMID: 33566465, PMCID: PMC7979442, DOI: 10.1097/ccm.0000000000004848.Peer-Reviewed Original ResearchConceptsCentral venous catheter-associated deep venous thrombosisCatheter-associated deep venous thrombosisCentral venous cathetersEfficacy of prophylaxisDeep venous thrombosisAge-dependent heterogeneityAnti-Xa levelsVenous cathetersVenous thrombosisFactor VIII activityThrombin generationPlatelet countClinical trialsIll childrenPhase 2bVIII activityLow factor VIII activityCatheter-Associated ThrombosisInternational units/mLMinimum platelet countOlder childrenCritically Ill ChildrenEndogenous thrombin potentialHigher platelet countsPost Hoc AnalysisUntwisting the complexity of midgut malrotation and volvulus ultrasound
Nguyen HN, Navarro OM, Guillerman RP, Silva CT, Sammer MBK. Untwisting the complexity of midgut malrotation and volvulus ultrasound. Pediatric Radiology 2021, 51: 658-668. PMID: 33398405, DOI: 10.1007/s00247-020-04876-x.Peer-Reviewed Original ResearchConceptsMidgut volvulusMidgut malrotationCommon conditionAcute abdominal signsUpper gastrointestinal seriesUpper GI seriesHypertrophic pyloric stenosisDiagnostic imaging testsOral contrast agentAbdominal signsAbdominal USGastrointestinal seriesGI seriesPrompt treatmentClinical presentationPyloric stenosisDiagnostic findingsImaging testsPictorial essayUS protocolVolvulusMalrotationContrast agentsEnterocolitisAppendicitis
2020
Efficacy of Early Prophylaxis Against Catheter-Associated Thrombosis in Critically Ill Children: A Bayesian Phase 2b Randomized Clinical Trial.
Faustino EVS, Shabanova V, Raffini LJ, Kandil SB, Li S, Pinto MG, Cholette JM, Hanson SJ, Nellis ME, Silva CT, Chima R, Sharathkumar A, Thomas KA, McPartland T, Tala JA, Spinella PC. Efficacy of Early Prophylaxis Against Catheter-Associated Thrombosis in Critically Ill Children: A Bayesian Phase 2b Randomized Clinical Trial. Critical Care Medicine 2020, 49: e235-e246. PMID: 33372745, PMCID: PMC7902342, DOI: 10.1097/ccm.0000000000004784.Peer-Reviewed Original ResearchConceptsCentral venous catheter-associated deep venous thrombosisCatheter-associated deep venous thrombosisDeep venous thrombosisUsual care armCentral venous cathetersVenous thrombosisClinical trialsEnoxaparin armCare armVenous cathetersEarly prophylaxisIll childrenThrombin generationPhase 2bCatheter-Associated ThrombosisInternational units/mLAnti-Xa levelsCritically Ill ChildrenRandomized clinical trialsEndogenous thrombin potentialRelevant bleedingUsual careTrial armsRisk ratioThrombin potentialPearls and Pitfalls in Pediatric Thyroid Imaging
Silva CT, Navarro OM. Pearls and Pitfalls in Pediatric Thyroid Imaging. Seminars In Ultrasound CT And MRI 2020, 41: 421-432. PMID: 32980089, DOI: 10.1053/j.sult.2020.05.007.Peer-Reviewed Original ResearchConceptsDiffuse thyroid enlargementThyroid enlargementCongenital hypothyroidismThyroid nodulesThyroid imagingPediatric age groupRole of imagingRisk of malignancyPermanent congenital hypothyroidismGraves' diseasePediatric populationHashimoto's diseaseNodular hyperplasiaPapillary carcinomaThyroid glandAccurate diagnosisAge groupsThyroid dysgenesisHypothyroidismDiseaseChildrenTeenage girlsImagingManagement recommendationsEnlargement
2019
Terminal Ileitis Presenting With a Spontaneously Reduced Ileocolic Intussusception Diagnosed by Point-of-Care Ultrasonography.
Riera A, Langhan M, Silva CT. Terminal Ileitis Presenting With a Spontaneously Reduced Ileocolic Intussusception Diagnosed by Point-of-Care Ultrasonography. Pediatric Emergency Care 2019, 36: e30-e32. PMID: 31433363, DOI: 10.1097/pec.0000000000001879.Peer-Reviewed Original ResearchConceptsIleocolic intussusceptionCare ultrasoundIschemic bowel injurySignificant inflammatory changesBowel injuryInitial workupInflammatory changesSurgical reductionTerminal ileitisTerminal ileumCare ultrasonographyRadiology ultrasoundIntussusceptionAcademic centersReduction attemptsSensitivity of studiesSpontaneous reductionTest characteristicsUltrasoundDiagnostic techniquesRadiologyIleitisUltrasonographyIleumInjuryReevaluation of FAST Sensitivity in Pediatric Blunt Abdominal Trauma Patients
Riera A, Hayward H, Silva C, Chen L. Reevaluation of FAST Sensitivity in Pediatric Blunt Abdominal Trauma Patients. Pediatric Emergency Care 2019, 37: e1012-e1019. PMID: 31356479, DOI: 10.1097/pec.0000000000001877.Peer-Reviewed Original ResearchConceptsBlunt abdominal trauma patientsAbdominal trauma patientsFree fluidTrauma patientsUpper quadrantPredictive valueLevel I pediatric trauma centerPediatric trauma centerRetrospective chart reviewRight upper quadrantFAST examinationNegative predictive valuePositive predictive valueNegative likelihood ratioChart reviewBAT patientsMedian ageTrauma centerUpper abdomenIntraperitoneal fluidMAIN OUTCOMEPhysiologic amountsTrauma (FAST) examinationPatientsFocused assessmentProviding Expert Pediatric Teleradiology Services Around the Globe: The World Federation of Pediatric Imaging Experience
Otero HJ, Andronikou S, Grassi DC, Silva CT. Providing Expert Pediatric Teleradiology Services Around the Globe: The World Federation of Pediatric Imaging Experience. Journal Of The American College Of Radiology 2019, 17: 53-55. PMID: 31278921, DOI: 10.1016/j.jacr.2019.06.006.Peer-Reviewed Original Research
2018
Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents
Faustino EVS, Shabanova V, Pinto MG, Li S, Trakas E, Miksa M, Gertz S, Polikoff LA, Napolitano M, Brudnicki AR, Tala JA, Silva CT, Investigators T, Miksa M, Taragin B, Blickman J, Taillie E, Trakas E, Balasco A, Herliczek T, Polikoff L, Dovi G, Napolitano M, Gertz S, Riordan M, Zasa J, Brudnicki A, Eldridge P, Li S, Pinto M, Faustino E, Silva C, Tala J. Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents. The Journal Of Pediatrics 2018, 201: 176-183.e2. PMID: 29891258, DOI: 10.1016/j.jpeds.2018.05.006.Peer-Reviewed Original ResearchConceptsDeep venous thrombosisExtremity deep venous thrombosisIll adolescentsVenous thrombosisFrequency of DVTLower extremity deep venous thrombosisCases of DVTBilateral deep venous thrombosisPediatric intensive care unitInvasive mechanical ventilationCentral venous catheterizationIntensive care unitPharmacologic prophylaxisTherapeutic anticoagulationCohort studyPulmonary embolismCardiopulmonary supportCare unitMechanical ventilationVenous catheterizationSevere illnessSerial sonogramsLower extremitiesEpidemiologyThrombosis
2017
Abusive fracture incidence over three decades at a level 1 pediatric trauma center
Sharkey MS, Buesser KE, Gaither JR, Tate V, Cooperman DR, Moles RL, Silva CT, Ehrlich LJ, Leventhal JM. Abusive fracture incidence over three decades at a level 1 pediatric trauma center. Child Abuse & Neglect 2017, 76: 364-371. PMID: 29195174, DOI: 10.1016/j.chiabu.2017.11.008.Peer-Reviewed Original ResearchConceptsPediatric trauma centerLevel 1 pediatric trauma centerAbusive fracturesTrauma centerED visitsSingle pediatric trauma centerSame trauma centerSingle-institution reviewFracture incidenceInstitution reviewEmergency departmentIncidenceAgeChildrenConsensus ratingsRecent dataTime periodVisitsFracturesCurrent studyRecent time periodPeriodGeographic regionsCenterStudyInter-rater reliability of physical abuse determinations in young children with fractures
Buesser KE, Leventhal JM, Gaither JR, Tate V, Cooperman DR, Moles RL, Silva CT, Ehrlich LJ, Sharkey MS. Inter-rater reliability of physical abuse determinations in young children with fractures. Child Abuse & Neglect 2017, 72: 140-146. PMID: 28802910, DOI: 10.1016/j.chiabu.2017.08.001.Peer-Reviewed Original ResearchConceptsChild abuse pediatriciansModerate agreementPediatric emergency departmentMedical record dataYoung childrenAbusive injuriesEmergency departmentJoint ratingsClinical detailsInter-rater reliabilityPediatric radiologistsClinical scenariosMedical providersPairs of ratersPediatric orthopaedistsLevel of agreementOrthopaedistsRecord dataCliniciansGold standardIndependent ratingsRadiologistsChildrenExtent of agreementPhysiciansAssessment of a modified technique for air delivery during fluoroscopic-monitored pneumatic intussusception reduction
Jindal G, Graeber BL, Staib LH, Silva CT. Assessment of a modified technique for air delivery during fluoroscopic-monitored pneumatic intussusception reduction. Pediatric Radiology 2017, 47: 1594-1598. PMID: 28681232, DOI: 10.1007/s00247-017-3920-z.Peer-Reviewed Original ResearchCongenital Cystic Lung Lesions
Hardee S, Tuzovic L, Silva CT, Cowles RA, Copel J, Morotti RA. Congenital Cystic Lung Lesions. Pediatric And Developmental Pathology 2017, 20: 403-410. PMID: 28812458, DOI: 10.1177/1093526617698604.Peer-Reviewed Original ResearchConceptsCongenital cystic lung lesionsCongenital pulmonary airway malformationCystic lung lesionsBronchopulmonary sequestrationLung lesionsPrenatal ultrasoundSingle tertiary care centerPulmonary airway malformationTertiary care centerFinal pathologic diagnosisCorrelate imagingCPAM lesionsAirway malformationExcellent prognosisPostnatal imagingRetrospective reviewPathological findingsPathology databaseRare pathologySurgical interventionBronchial atresiaPrenatal coursePathologic diagnosisPathology examinationCare center
2015
Duodenal intussusception secondary to web presenting as recurrent pancreatitis in a 7-year-old girl
Tu LH, Villalona GA, Cowles RA, Silva CT. Duodenal intussusception secondary to web presenting as recurrent pancreatitis in a 7-year-old girl. Pediatric Radiology 2015, 46: 426-429. PMID: 26553449, DOI: 10.1007/s00247-015-3481-y.Peer-Reviewed Original ResearchDiagnostic accuracy of point-of-care ultrasound for catheter-related thrombosis in children
Li S, Silva CT, Brudnicki AR, Baker KE, Tala JA, Pinto MG, Polikoff LA, Qin L, Faustino EV, Northeast Pediatric Critical Care Research Consortium. Diagnostic accuracy of point-of-care ultrasound for catheter-related thrombosis in children. Pediatric Radiology 2015, 46: 219-228. PMID: 26440129, PMCID: PMC4738063, DOI: 10.1007/s00247-015-3467-9.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionCausalityCentral Venous CathetersChildChild, PreschoolCohort StudiesConnecticutFemaleHumansInfantInfant, NewbornMalePoint-of-Care TestingPrevalenceReproducibility of ResultsRisk FactorsSensitivity and SpecificitySex DistributionUltrasonographyUpper Extremity Deep Vein ThrombosisConceptsCatheter-related thrombosisCare ultrasoundChance-corrected agreementIll childrenCare USCentral venous catheter-related thrombosisPediatric radiologistsDeep venous thrombosisCentral venous cathetersIntensive care unitVenous cathetersVenous thrombosisCare unitSubclavian veinThrombosisAccuracy of pointCatheterSensitivity of pointDiscordant readingsDiagnostic accuracyMulticenterUltrasoundRadiology departmentChildrenPhysiciansFactor VIII May Predict Catheter-Related Thrombosis in Critically Ill Children
Faustino EV, Li S, Silva CT, Pinto MG, Qin L, Tala JA, Rinder HM, Kupfer GM, Shapiro ED. Factor VIII May Predict Catheter-Related Thrombosis in Critically Ill Children. Pediatric Critical Care Medicine 2015, 16: 497-504. PMID: 25828784, PMCID: PMC4497863, DOI: 10.1097/pcc.0000000000000409.Peer-Reviewed Original ResearchConceptsCatheter-related thrombosisFactor VIII activityIncident thrombosisIll childrenVIII activityCentral venous catheter-related thrombosisDays of enrollmentProspective cohort studyCentral venous cathetersImportant clinical predictorsTertiary academic centerIU/dlPharmacologic thromboprophylaxisSurveillance ultrasonographyCohort studyVenous cathetersClinical predictorsThrombotic eventsOdds ratioSD increaseHigh riskThrombosisAcademic centersFactor VIIIYouden indexPrevalence of post‐thrombotic syndrome after cardiac catheterization
Luceri MJ, Tala JA, Weismann CG, Silva CT, Faustino EV. Prevalence of post‐thrombotic syndrome after cardiac catheterization. Pediatric Blood & Cancer 2015, 62: 1222-1227. PMID: 25663038, PMCID: PMC4433560, DOI: 10.1002/pbc.25438.Peer-Reviewed Original ResearchConceptsPost-thrombotic syndromeCardiac catheterizationFirst catheterizationCyanotic congenital heart diseaseManco-Johnson instrumentDeep venous thrombosisSurvival of childrenTime of enrollmentCongenital heart diseaseCross-sectional studyChronic complicationsCommon complicationMedian ageVenous thrombosisValvular insufficiencyFemoral veinHeart diseaseSignificant syndromeAntithrombotic agentsCatheterizationSyndromeDisease increasesThrombosisComplicationsChildren
2014
Postnatal sonographic spectrum of prenatally detected abdominal and pelvic cysts.
Silva CT, Engel C, Cross SN, Copel JE, Morotti RA, Baker KE, Goodman TR. Postnatal sonographic spectrum of prenatally detected abdominal and pelvic cysts. American Journal Of Roentgenology 2014, 203: w684-96. PMID: 25415735, DOI: 10.2214/ajr.13.12371.Peer-Reviewed Original Research