2019
Red blood cell alloimmunization is associated with lower expression of FcγR1 on monocyte subsets in patients with sickle cell disease
Balbuena‐Merle R, Curtis SA, Devine L, Gibb DR, Karafin MS, Luckey CJ, Tormey CA, Siddon AJ, Roberts JD, Hendrickson JE. Red blood cell alloimmunization is associated with lower expression of FcγR1 on monocyte subsets in patients with sickle cell disease. Transfusion 2019, 59: 3219-3227. PMID: 31355970, PMCID: PMC7075520, DOI: 10.1111/trf.15463.Peer-Reviewed Original ResearchConceptsSickle cell diseaseMonocyte subsetsTotal monocytesCell diseaseComplications of SCDRed blood cell alloimmunizationRed blood cell alloantibodiesElectronic medical recordsTransfusion exposureSerum cytokinesIntermediate monocytesRBC alloantibodiesInflammatory milieuCD64 expressionClassical monocytesPeripheral bloodInflammatory functionsMedical recordsAntibody formationClinical significancePatientsMonocytesFlow cytometryLow expressionResponders
2016
Estimating the immunogenicity of blood group antigens: a modified calculation that corrects for transfusion exposures
Stack G, Tormey CA. Estimating the immunogenicity of blood group antigens: a modified calculation that corrects for transfusion exposures. British Journal Of Haematology 2016, 175: 154-160. PMID: 27340943, DOI: 10.1111/bjh.14175.Peer-Reviewed Original ResearchConceptsAntigen immunogenicityPre-existing antibodiesLow-frequency antigensMean RBCHigh-frequency antigensHospital transfusion servicesTransfusion exposureAntibody frequencyAntigen exposureRBC exposureTransfusion servicesImmunogenicityRBC unitsAntigenPatientsBlood groupReference antigenUnit exposureExposureFold increaseSmall increase