2023
Pleiotropic Association of CACNA1C Variants With Neuropsychiatric Disorders
Wang Z, Lin X, Luo X, Xiao J, Zhang Y, Xu J, Wang S, Zhao F, Wang H, Zheng H, Zhang W, Lin C, Tan Z, Cao L, Wang Z, Tan Y, Chen W, Cao Y, Guo X, Pittenger C, Luo X. Pleiotropic Association of CACNA1C Variants With Neuropsychiatric Disorders. Schizophrenia Bulletin 2023, 49: 1174-1184. PMID: 37306960, PMCID: PMC10483336, DOI: 10.1093/schbul/sbad073.Peer-Reviewed Original ResearchConceptsGray matter volumeBipolar disorderNeuropsychiatric disordersIntracranial volumeSingle nucleotide polymorphismsParkinson's diseaseCACNA1C variantsCACNA1C mRNARisk allelesAlcohol use disorderAverage cortical thicknessTotal intracranial volumeMultiple psychiatric disordersFalse discovery rate correctionDifferent neuropsychiatric disordersCortical surface areaBrain cohortCortical thicknessIndependent cohortPsychiatric disordersUse disordersMatter volumeSubcortical structuresSubstance dependenceDiseaseNeuroinflammation in Obsessive-Compulsive Disorder Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, and Pediatric Acute Onset Neuropsychiatric Syndrome
Vreeland A, Thienemann M, Cunningham M, Muscal E, Pittenger C, Frankovich J. Neuroinflammation in Obsessive-Compulsive Disorder Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, and Pediatric Acute Onset Neuropsychiatric Syndrome. Psychiatric Clinics Of North America 2023, 46: 69-88. PMID: 36740356, DOI: 10.1016/j.psc.2022.11.004.Peer-Reviewed Original ResearchConceptsPediatric acute-onset neuropsychiatric syndromePediatric autoimmune neuropsychiatric disordersAutoimmune neuropsychiatric disordersSydenham's choreaStreptococcal infectionNeuroinflammatory diseasesNeuropsychiatric syndromeNeuropsychiatric disordersSource of inflammationObsessive-compulsive disorderRheumatological diseasesBasal gangliaClinical trialsClinical dataMajor manifestationsDiagnostic biomarkersImmune systemDisordersDiseaseBehavioral disordersInflammationChoreaSyndromeInfectionFuture studies
2015
Are There Biological Commonalities Among Different Psychiatric Disorders?
Etkin A, Pittenger C. Are There Biological Commonalities Among Different Psychiatric Disorders? 2015, 243-257. DOI: 10.1002/9781118753378.ch15.Peer-Reviewed Original ResearchPsychiatric diseasesDifferent disordersMajor depressive disorderSame brain circuitsDifferent psychiatric disordersAnterior cingulate cortexDorsolateral prefrontal cortexDepressive disorderDorsal striatumPsychiatric disordersCingulate cortexOverlapping symptomatologyBrain circuitsVentral striatumBiological commonalitiesBrain functionPrefrontal cortexDisordersNormal functionDrug addictionStriatumCortexDiseaseDiagnosisSymptomatology