2022
Hypothalamic Functional Connectivity and Apathy in People with Alzheimer’s Disease and Cognitively Normal Healthy Controls
Chaudhary S, Zhornitsky S, Chao H, van Dyck C, Li C. Hypothalamic Functional Connectivity and Apathy in People with Alzheimer’s Disease and Cognitively Normal Healthy Controls. Journal Of Alzheimer's Disease 2022, 90: 1615-1628. PMID: 36314209, PMCID: PMC10064487, DOI: 10.3233/jad-220708.Peer-Reviewed Original ResearchConceptsMiddle temporal gyrusMild cognitive impairmentMotivation circuitsFunctional connectivityPath analysisWhole-brain regressionPCu/PCCState functional connectivityTotal scoreTemporal gyrusNeural markersCingulate cortexMemory dysfunctionRSFCHealthy controlsCognitive statusCognitive impairmentAlzheimer's diseaseApathyPrecuneusMemoryRsFCsDepressionScale total scoreCognitive subscores
2021
Symptom provocation in obsessive–compulsive disorder: A voxel-based meta-analysis and meta-analytic connectivity modeling
Yu J, Zhou P, Yuan S, Wu Y, Wang C, Zhang N, Li CR, Liu N. Symptom provocation in obsessive–compulsive disorder: A voxel-based meta-analysis and meta-analytic connectivity modeling. Journal Of Psychiatric Research 2021, 146: 125-134. PMID: 34971910, DOI: 10.1016/j.jpsychires.2021.12.029.Peer-Reviewed Original ResearchConceptsRight lateral occipital gyrusMiddle occipital gyrusMiddle cingulate cortexLateral occipital gyrusRight caudate bodyMiddle temporal gyrusObsessive-compulsive disorderInferior frontal gyrusSymptom provocationOCD patientsOrbitofrontal cortexCaudate bodyPrimary analysisThalamic-cortical circuit [CSTC] dysfunctionOccipital gyrusPosterior cortical structuresMagnetic resonance imaging studyActivation likelihood estimation algorithmHigher activationRight middle temporal gyrusRight orbitofrontal cortexLeft orbitofrontal cortexResonance imaging studyFunctional magnetic resonance imaging studyDorsal striatal activation
2020
The Long‐Term Effects of Acupuncture on Hippocampal Functional Connectivity in aMCI with Hippocampal Atrophy: A Randomized Longitudinal fMRI Study
Li H, Wang Z, Yu H, Pang R, Ni H, Li C, Li K. The Long‐Term Effects of Acupuncture on Hippocampal Functional Connectivity in aMCI with Hippocampal Atrophy: A Randomized Longitudinal fMRI Study. Neural Plasticity 2020, 2020: 1-9. DOI: 10.1155/2020/6389368.Peer-Reviewed Original ResearchHippocampal functional connectivityAmnestic mild cognitive impairmentAcupuncture treatmentAcupuncture groupLong-term effectsFunctional magnetic resonance imagingFunctional connectivityControl groupAMCI patientsWhole-brain FC analysisResting-state functional magnetic resonance imagingResting-state fMRI scanningLongitudinal fMRI studyMagnetic resonance imagingHealthy control participantsMild cognitive impairmentMiddle temporal gyrusAcupuncture patientsHippocampal atrophyTherapeutic roleRight hippocampusBilateral caudateFC strengthAcupunctureCognitive decline
2018
Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study
Li H, Jia X, Qi Z, Fan X, Ma T, Pang R, Ni H, Li CR, Lu J, Li K. Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study. Frontiers In Human Neuroscience 2018, 12: 413. PMID: 30420801, PMCID: PMC6216144, DOI: 10.3389/fnhum.2018.00413.Peer-Reviewed Original ResearchAmnestic mild cognitive impairmentMiddle temporal gyrusRight middle temporal gyrusState functional connectivityMild cognitive impairmentFunctional connectivityAMCI subjectsRight CA1Cornu ammonisLongitudinal resting-state fMRI studyCognitive impairmentCuneal cortexLongitudinal changesResting-State fMRI StudyState functional MRI scansDisrupted Functional ConnectivityLongitudinal cognitive assessmentsFunctional MRI scansGray matter volumeSubtle structural deficitsHealthy control participantsMiddle temporal cortexImportant neural markerCovariates of ageCA1 connectivity