2016
A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion
Xu W, Nathwani B, Lin C, Wang J, Karatekin E, Pincet F, Shih W, Rothman JE. A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion. Journal Of The American Chemical Society 2016, 138: 4439-4447. PMID: 26938705, PMCID: PMC4950518, DOI: 10.1021/jacs.5b13107.Peer-Reviewed Original ResearchMeSH KeywordsDNADNA, Single-StrandedLipid BilayersLiposomesMembrane FusionProtein BindingSNARE ProteinsVesicular Transport ProteinsConceptsMembrane fusionSoluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexCore molecular machineryMembrane fusion eventsProtein receptor complexMembrane fusion processMolecular machineryDNA origami platformTarget membraneAuxiliary proteinsIntracellular communicationDocking stepSingle-event levelReceptor complexLipid mixingSmall unilamellar vesiclesLipid bilayersSnareFundamental processesVesiclesUnilamellar vesiclesTraffickingMachineryProteinFusion
2011
Synthesis and Characterization of Self-Assembled DNA Nanostructures
Lin C, Ke Y, Chhabra R, Sharma J, Liu Y, Yan H. Synthesis and Characterization of Self-Assembled DNA Nanostructures. Methods In Molecular Biology 2011, 749: 1-11. PMID: 21674361, DOI: 10.1007/978-1-61779-142-0_1.ChaptersMeSH KeywordsDNA, Single-StrandedElectrophoresisMicroscopy, Atomic ForceNanostructuresNanotechnologyNucleic Acid ConformationOligonucleotidesConceptsDNA nanostructuresDNA nanotechnologySelf-assembled DNA nanostructuresSuch nanoscale objectsStructural DNA nanotechnologyCharacterization of SelfDNA-based nanodevicesExcellent yieldsNanoscale objectsNanostructuresArtificial nanostructuresMolecular speciesBuilding blocksNanotechnologyFast evolvementMain building blocksNanoarchitecturesLarge varietySynthesisMaterialsNanodevicesPreparationCharacterizationBuilding materialsYield
2009
A Replicable Tetrahedral Nanostructure Self-Assembled from a Single DNA Strand
Li Z, Wei B, Nangreave J, Lin C, Liu Y, Mi Y, Yan H. A Replicable Tetrahedral Nanostructure Self-Assembled from a Single DNA Strand. Journal Of The American Chemical Society 2009, 131: 13093-13098. PMID: 19737020, PMCID: PMC3083857, DOI: 10.1021/ja903768f.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceCloning, MolecularDNA ReplicationDNA, Single-StrandedModels, MolecularMolecular Sequence DataNanostructuresNucleic Acid ConformationConceptsAtomic force microscopy imagingForce microscopy imagingRolling-circle amplificationDNA nanostructuresSingle DNA strandsFerguson analysisMicroscopy imagingTetrahedraStandard molecular cloning techniquesDNA strandsSingle strandsRestriction enzyme digestionCloning techniquesMolecular cloning techniques