2020
DNA Origami Post‐Processing by CRISPR‐Cas12a
Xiong Q, Xie C, Zhang Z, Liu L, Powell JT, Shen Q, Lin C. DNA Origami Post‐Processing by CRISPR‐Cas12a. Angewandte Chemie International Edition 2020, 59: 3956-3960. PMID: 31883145, PMCID: PMC7101258, DOI: 10.1002/anie.201915555.Peer-Reviewed Original ResearchConceptsDNA origami structuresCRISPR-Cas12aDNA origami devicesDNA origami designDNA origami techniqueNanomaterial fabricationFunctional nanodevicesDNA origamiScaffold strandTremendous promiseCutting-edge toolsVersatile toolNanodevicesNanostructuresFacileFabricationBiocompatibilityBiotechnologySequence specificityOrigamiEnzymatic methodMechanical propertiesStructural transformationDevicesIntricate structure
2018
Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape
Bastings MMC, Anastassacos FM, Ponnuswamy N, Leifer FG, Cuneo G, Lin C, Ingber DE, Ryu JH, Shih WM. Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape. Nano Letters 2018, 18: 3557-3564. PMID: 29756442, DOI: 10.1021/acs.nanolett.8b00660.Peer-Reviewed Original ResearchConceptsDNA nanotechnologyStructural DNA nanotechnologyThree-dimensional nanostructuresCellular uptakeDNA origami shapesDesigner nanoparticlesNanoparticle uptakeDNA origamiCell delivery vehicleTherapeutic deliveryAttractive platformCell uptakeNanotechnologyNanoparticlesGreater compactnessDifferent cell linesUnparalleled abilityNanostructuresResolution featuresLarge particlesLimited controlParticle shapeOrigamiRatio particlesParticles