2011
Survivin Inhibition Is Critical for Bcl-2 Inhibitor-Induced Apoptosis in Hepatocellular Carcinoma Cells
Zhao X, Ogunwobi O, Liu C. Survivin Inhibition Is Critical for Bcl-2 Inhibitor-Induced Apoptosis in Hepatocellular Carcinoma Cells. PLOS ONE 2011, 6: e21980. PMID: 21829603, PMCID: PMC3148218, DOI: 10.1371/journal.pone.0021980.Peer-Reviewed Original ResearchConceptsBcl-2 inhibitorsCombination treatmentHCC cellsABT-263Survivin inhibitionHepatocellular carcinomaHuman liver cancer tissuesSingle treatmentFuture clinical trialsApoptotic effectsLiver cancer tissuesLiver cancer therapyERK activationHCC cell linesHepatocellular carcinoma cellsPreclinical dataClinical trialsTherapeutic effectLow doseNormal human hepatocytesCancer tissuesYM-155High dosesNovel Bcl-2 inhibitorABT-263-induced apoptosis
1998
Cloning and expression of a cDNA encoding the large subunit of duck replication factor C1Genbank accession number: U60144.1
Guo J, Liu C, Mason W, Pugh J. Cloning and expression of a cDNA encoding the large subunit of duck replication factor C1Genbank accession number: U60144.1. Biochimica Et Biophysica Acta 1998, 1395: 293-300. PMID: 9512663, DOI: 10.1016/s0167-4781(97)00174-7.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsBacteriophage lambdaBase SequenceCloning, MolecularDNA ReplicationDNA-Binding ProteinsDNA, ComplementaryDrosophilaDucksGene LibraryHomeodomain ProteinsHumansLiverMacromolecular SubstancesMiceMinor Histocompatibility AntigensMolecular Sequence DataMolecular WeightProto-Oncogene Proteins c-bcl-2Replication Protein CRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence AlignmentSequence Homology, Amino Acid