CEACAM-1 Is Involved in Graft-Versus-Host-Disease in Murine Allogeneic Bone Marrow Transplantation Models.
Lu S, Willis L, Smith M, Suh D, King C, Bautista J, Chow M, Cabrera-Perez J, Hubbard V, Rotolo J, Liu C, Murphy G, Alpdogan O, Blumberg R, Holmes K, Turbide C, Beauchemin N, van den Brink M. CEACAM-1 Is Involved in Graft-Versus-Host-Disease in Murine Allogeneic Bone Marrow Transplantation Models. Blood 2007, 110: 67. DOI: 10.1182/blood.v110.11.67.67.Peer-Reviewed Original ResearchWT T cellsT cellsWT recipientsAdoptive transferSmall bowelMurine allogeneic bone marrow transplantation modelWT controlsAllogeneic bone marrow transplantation modelCarcinoembryonic antigenSplenic regulatory T cellsAllogeneic bone marrow transplantationCEACAM-1Cell adhesion molecule-1Conditioning-related toxicityDonor T cellsGVHD target organsPeripheral lymph nodesRegulatory T cellsAlloreactive T cellsBone marrow transplantation modelBone marrow transplantationDonor bone marrowAdhesion molecule-1T cell apoptosisT cell activation