Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells
Yao L, Yan X, Dong H, Nelson D, Liu C, Li X. Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells. Virology Journal 2011, 8: 445. PMID: 21936899, PMCID: PMC3213043, DOI: 10.1186/1743-422x-8-445.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineDEAD Box Protein 58DEAD-box RNA HelicasesGene ExpressionHepacivirusHepatocytesHumansInterferon Regulatory Factor-3Interferon-alphaInterferon-betaMiceProtein BiosynthesisProtein MultimerizationReal-Time Polymerase Chain ReactionReceptors, EstrogenReceptors, ImmunologicRecombinant Fusion ProteinsTranscription, GeneticVirus ReplicationConceptsAnti-HCV effectInterferon regulatory factor 3Huh-7.5 cellsEstrogen receptorPolymerase chain reactionHepatitis C virus infectionViral replicationC virus infectionMouse estrogen receptorHepatitis C viral replicationInterferon-stimulated gene expressionExpression of IFNHCV viral replicationHCV RNA replicationReal-time polymerase chain reactionEstrogen receptor agonistsExpression of ISGsRegulatory factor 3HCV IRES-dependent translation