2012
Hepatocyte Paraffin 1 Antigen as a Biomarker for Early Diagnosis of Barrett Esophagus
Jeung J, Coran J, Liu C, Cardona D. Hepatocyte Paraffin 1 Antigen as a Biomarker for Early Diagnosis of Barrett Esophagus. American Journal Of Clinical Pathology 2012, 137: 111-120. PMID: 22180484, PMCID: PMC3806975, DOI: 10.1309/ajcpyobvgs4cga8y.Peer-Reviewed Original ResearchConceptsBarrett's esophagusBE casesMorphologic changesIntestinal differentiationReflux esophagitis casesSmall intestinal differentiationMetaplastic reactionCertain morphologic changesClinicopathologic featuresIntestinal metaplasiaAntigen expressionEarly diagnosisSensitive markerBiopsy casesGoblet cellsMorphologic featuresRE casesEsophagusExpressionMetaplasiaHepPar1CasesInjuryAntigenDiagnosis
2008
Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells
Shangguan D, Meng L, Cao Z, Xiao Z, Fang X, Li Y, Cardona D, Witek R, Liu C, Tan W. Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells. Analytical Chemistry 2008, 80: 721-728. PMID: 18177018, DOI: 10.1021/ac701962v.Peer-Reviewed Original ResearchConceptsLiver cancerLiver cancer cellsEarly diagnosisCell linesBALB/cJ miceCancer cellsSurgical resectionClinical outcomesLiver cell lineEffective treatmentMouse modelWhole live cellsDeadly cancerCurrent studyCancer-specific aptamersTumor selectionBasic mechanism studiesCancerMost cancersBNL CLCancer early diagnosisCell-SELEX methodNoncancer cell linesDiagnosisCancer recognition