2016
Development of an Interception Glove Sampler for Skin Exposures to Aromatic Isocyanates
Harari H, Bello D, Woskie S, Redlich C. Development of an Interception Glove Sampler for Skin Exposures to Aromatic Isocyanates. Annals Of Work Exposures And Health 2016, 60: 1092-1103. PMID: 27694341, DOI: 10.1093/annhyg/mew052.Peer-Reviewed Original Research
2010
Skin Exposure and Asthma
Redlich CA. Skin Exposure and Asthma. Annals Of The American Thoracic Society 2010, 7: 134-137. PMID: 20427586, PMCID: PMC3266020, DOI: 10.1513/pats.201002-025rm.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAllergensAsthmaDermatitis, AtopicEnvironmental ExposureFilaggrin ProteinsHumansSkin AbsorptionConceptsSkin exposureSite of sensitizationSubsequent inhalation challengeAsthma risk factorsImpair skin barrier functionFilaggrin gene mutationsSkin barrier functionAllergen entryAsthmatic responseInhalation challengeSubsequent asthmaAsthma developmentRisk factorsRespiratory tractHuman skin exposureAsthma riskSkin traumaAnimal studiesEpidemiology studiesBarrier functionEnvironmental exposuresGene mutationsProtein allergensSensitizationExposure assessment
2008
Lung/skin connections in occupational lung disease
Redlich CA, Herrick CA. Lung/skin connections in occupational lung disease. Current Opinion In Allergy And Clinical Immunology 2008, 8: 115-119. PMID: 18317018, DOI: 10.1097/aci.0b013e3282f85a31.Peer-Reviewed Original ResearchConceptsOccupational lung diseaseLung diseaseChronic beryllium diseaseSkin exposureIsocyanate asthmaBeryllium diseaseSite of sensitizationSubsequent inhalation challengeEnvironmental lung diseaseLimited clinical studiesImpair skin barrier functionSkin barrier functionAsthmatic responseInhalation challengeRespiratory tractHuman skin exposureClinical studiesInhalation exposureRecent studiesAnimal studiesAirborne exposureDiseaseBarrier functionPersonal protective clothingProtein allergensSkin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: II. A Quantitative Assessment
Bello D, Redlich CA, Stowe MH, Sparer J, Woskie SR, Streicher RP, Hosgood HD, Liu Y. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: II. A Quantitative Assessment. Annals Of Work Exposures And Health 2008, 52: 117-124. PMID: 18209009, DOI: 10.1093/annhyg/mem066.Peer-Reviewed Original ResearchConceptsSkin exposureUnprotected skinAuto body shop workersAuto Body RepairRespiratory exposureSkin areasExposure dataShop workersSkin samplingSkinExposureWipe samplesUnpaired samplesHigh concentrationsPPEGm loadYale studyHigh levelsBody repairAsthmaMajor contributorLevelsQuantitative assessmentForearmSensitization
2007
Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: A Qualitative Assessment
LIU Y, BELLO D, SPARER JA, STOWE MH, GORE RJ, WOSKIE SR, CULLEN MR, REDLICH CA. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: A Qualitative Assessment. Annals Of Work Exposures And Health 2007, 51: 429-439. PMID: 17602207, DOI: 10.1093/annhyg/mem021.Peer-Reviewed Original ResearchConceptsAuto body shop workersSkin exposureHigh-performance liquid chromatographyShop workersHigher positive rateAuto Body RepairPositive surface samplesPositive sample rateEpidemiologic studiesUnprotected skinRespiratory exposurePercent of samplesSensitive high-performance liquid chromatographyLatex glovesScale 0Exposure dataExposure determinantsSkin samplesQuantitative high-performance liquid chromatographyNational InstituteOccupational SafetyAuto body shopsExposureMajor determinantPositive rate
2006
Skin Exposure to Isocyanates: Reasons for Concern
Bello D, Herrick CA, Smith TJ, Woskie SR, Streicher RP, Cullen MR, Liu Y, Redlich CA. Skin Exposure to Isocyanates: Reasons for Concern. Environmental Health Perspectives 2006, 115: 328-335. PMID: 17431479, PMCID: PMC1849909, DOI: 10.1289/ehp.9557.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAir Pollutants, OccupationalAnimalsAsthmaHumansIsocyanatesOccupational DiseasesOccupational ExposureSkinSkin AbsorptionConceptsSkin exposureIsocyanate asthmaSuch exposureAsthma-like responsesSubsequent inhalation challengeOccupational SafetyPersonal protective equipmentInhalation challengeOccupational asthmaSystemic sensitizationAsthmaInhalation exposureHealth AdministrationComputerized searchRespiratory exposureRelevant articlesProtective equipmentHuman literatureSkin absorptionSensitizationGoogle databasesNational InstituteLines of evidencePotential roleSufficient evidenceAn FTIR investigation of isocyanate skin absorption using in vitro guinea pig skin
Bello D, Smith TJ, Woskie SR, Streicher RP, Boeniger MF, Redlich CA, Liu Y. An FTIR investigation of isocyanate skin absorption using in vitro guinea pig skin. Environmental Science Processes & Impacts 2006, 8: 523-529. PMID: 16688353, DOI: 10.1039/b517948c.Peer-Reviewed Original ResearchConceptsMethylenediphenyl diisocyanateIsocyanate groupsTotal reflectance Fourier transformReflectance Fourier transformHexamethylene diisocyanate isocyanurateTotal isocyanate groupFTIR investigationAromatic isocyanatesGuinea pig skinChemical groupsIsocyanatesUnreacted speciesSmall compoundsUnreacted compoundsDermal exposureEthyl acetateIsocyanurateHairless guinea pig skinPig skinCompoundsSkin surfaceContact dermatitisDecontamination strategiesResidence timeSkin absorption