2009
Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating Factor
Toy EP, Azodi M, Folk NL, Zito CM, Zeiss CJ, Chambers SK. Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating Factor. Neoplasia 2009, 11: 136-144. PMID: 19177198, PMCID: PMC2631138, DOI: 10.1593/neo.81150.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkers, TumorCell AdhesionCell MovementCell Transformation, NeoplasticFemaleHumansMacrophage Colony-Stimulating FactorMiceMice, NudeNeoplasm InvasivenessNeoplasm MetastasisNeoplasm TransplantationNeoplasms, ExperimentalOligonucleotides, AntisenseOvarian NeoplasmsPhenotypeReceptor, Macrophage Colony-Stimulating FactorTumor Cells, Cultured
2005
Correlation of tumor phenotype with c-fms proto-oncogene expression in an in vivo intraperitoneal model for experimental human breast cancer metastasis
Toy EP, Bonafé N, Savlu A, Zeiss C, Zheng W, Flick M, Chambers SK. Correlation of tumor phenotype with c-fms proto-oncogene expression in an in vivo intraperitoneal model for experimental human breast cancer metastasis. Clinical & Experimental Metastasis 2005, 22: 1-9. PMID: 16132573, DOI: 10.1007/s10585-005-0718-4.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBreast NeoplasmsCarcinomaCell Line, TumorDexamethasoneDisease Models, AnimalFemaleGene ExpressionHormone AntagonistsHumansMiceMice, Inbred BALB CMice, SCIDMifepristonePeritoneal CavityPhenotypeProto-Oncogene MasReceptor, Macrophage Colony-Stimulating FactorUp-RegulationConceptsBALB/cProto-oncogene expressionC-fms proto-oncogene expressionExpression groupAthymic BALB/cHuman breast cancer metastasisIntraperitoneal modelBreast cancer metastasisHuman breast carcinoma cellsBreast carcinoma cellsClinical outcomesClinical evidenceTumor sizeC-fmsIntrasplenic injectionPrimary tumorMetastatic spreadOral administrationRU 486SCID miceBreast carcinomaSCID animalsImmunodeficient miceIHC stainingNovel treatments