2018
Measuring theory of mind in schizophrenia research: Cross-cultural validation
Lee HS, Corbera S, Poltorak A, Park K, Assaf M, Bell MD, Wexler BE, Cho YI, Jung S, Brocke S, Choi KH. Measuring theory of mind in schizophrenia research: Cross-cultural validation. Schizophrenia Research 2018, 201: 187-195. PMID: 29958750, DOI: 10.1016/j.schres.2018.06.022.Peer-Reviewed Original ResearchConceptsSocial Attribution Task-Multiple ChoiceTheory of mindSocial cognition measuresSocial cognition tasksSocial cognitive impairmentsSchizophrenia researchInternal consistencyConvergent/divergent validityConfirmatory factor analysisGood internal consistencyOne-factor modelCognition measuresCognition tasksIndividual differencesGood model fitCross-cultural validationMental statesMeasurement invarianceDivergent validityDiscriminant validityToMFactor structureHealthy controlsCognitive impairmentDiverse languages
2013
Factor Structure of Social Cognition in Schizophrenia: Is Empathy Preserved?
Corbera S, Wexler BE, Ikezawa S, Bell MD. Factor Structure of Social Cognition in Schizophrenia: Is Empathy Preserved? Schizophrenia Research And Treatment 2013, 2013: 409205. PMID: 24455254, PMCID: PMC3876916, DOI: 10.1155/2013/409205.Peer-Reviewed Original ResearchBasic social cognitionSocial cognitionInterpersonal discomfortCognitive processing deficitsSocial cognitive impairmentsSocial cognitive measuresSocial cognitive interventionsCognitive interventionsCognitive measuresProcessing deficitsLower social performanceCognitionSocial interactionCore featuresEmpathyFactor structureCognitive impairmentLower scoresNeurocognitionHigher scoresSocial functionSocial performanceSpecific aspectsSchizophreniaPoor functional outcome
2012
Computerized cognitive remediation training for schizophrenia: An open label, multi-site, multinational methodology study
Murthy NV, Mahncke H, Wexler BE, Maruff P, Inamdar A, Zucchetto M, Lund J, Shabbir S, Shergill S, Keshavan M, Kapur S, Laruelle M, Alexander R. Computerized cognitive remediation training for schizophrenia: An open label, multi-site, multinational methodology study. Schizophrenia Research 2012, 139: 87-91. PMID: 22342330, DOI: 10.1016/j.schres.2012.01.042.Peer-Reviewed Original ResearchConceptsFunctional capacity outcome measuresCognitive Assessment InterviewBrain Fitness ProgramSignificant treatment effectOutcome measuresRegular antipsychotic medicationStable adult patientsNon-pharmacological methodsCognitive performanceTreatment effectsComputerized cognitive remediation trainingMultinational clinical trialsSingle-site studyTraining effectsCognitive remediation trainingOpen labelAdult patientsAntipsychotic medicationCAI scoreClinical trialsCognitive impairmentMulti-site studyExercise taskRemediation trainingNeuropsychological tasks
2011
Social Cognitive Impairments and Negative Symptoms in Schizophrenia: Are There Subtypes With Distinct Functional Correlates?
Bell MD, Corbera S, Johannesen JK, Fiszdon JM, Wexler BE. Social Cognitive Impairments and Negative Symptoms in Schizophrenia: Are There Subtypes With Distinct Functional Correlates? Schizophrenia Bulletin 2011, 39: 186-196. PMID: 21976710, PMCID: PMC3523908, DOI: 10.1093/schbul/sbr125.Peer-Reviewed Original ResearchConceptsHigher social cognitionLower social cognitionSocial cognitive impairmentsHigh-negative symptom groupSocial cognitionNegative-symptom groupNegative symptomsCaruso Emotional Intelligence TestSocial cognitive measuresEmotional Intelligence TestSocial cognitive factorsCognitive impairmentSymptom groupsNegative symptom factorMayer-SaloveyCommon assessment instrumentsCognitive factorsCognitive measuresSubstance abuse historyIntelligence testsCore featuresAbuse historyIndependent dimensionsDistinct factorsSymptom factors
2010
Social attribution test — multiple choice (SAT-MC) in schizophrenia: Comparison with community sample and relationship to neurocognitive, social cognitive and symptom measures
Bell MD, Fiszdon JM, Greig TC, Wexler BE. Social attribution test — multiple choice (SAT-MC) in schizophrenia: Comparison with community sample and relationship to neurocognitive, social cognitive and symptom measures. Schizophrenia Research 2010, 122: 164-171. PMID: 20400268, PMCID: PMC2908733, DOI: 10.1016/j.schres.2010.03.024.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceChoice BehaviorCognition DisordersDisability EvaluationFemaleHumansInterpersonal RelationsLogistic ModelsMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesReproducibility of ResultsResidence CharacteristicsROC CurveSchizophreniaSchizophrenic PsychologySocial PerceptionConceptsSocial Attribution Task-Multiple ChoiceSocial cognitive measuresCognitive measuresAffect recognitionCommunity sampleSocial cognitive impairmentsTheory of mindSignificant group differencesMATRICS batteryNeurocognitive measuresSCZ participantsVerbal processesAutism researchCognition indexLongitudinal designSymptom measuresGroup differencesCognitive impairmentCommunity-dwelling participantsGeometric figuresSchizoaffective disorderParticipantsSchizophreniaImpairmentMultiple-choice questions
2008
Neurocognitive enhancement therapy with vocational services: Work outcomes at two-year follow-up
Bell MD, Zito W, Greig T, Wexler BE. Neurocognitive enhancement therapy with vocational services: Work outcomes at two-year follow-up. Schizophrenia Research 2008, 105: 18-29. PMID: 18715755, DOI: 10.1016/j.schres.2008.06.026.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognition DisordersCognitive Behavioral TherapyCombined Modality TherapyEmploymentEmployment, SupportedFemaleFollow-Up StudiesHumansMaleNeuropsychological TestsOccupational TherapyPsychiatric Status Rating ScalesPsychotherapy, GroupPsychotic DisordersRehabilitation, VocationalSchizophreniaSchizophrenic PsychologyTreatment OutcomeVocational EducationConceptsNeurocognitive enhancement therapyEnhancement therapyComputer-based cognitive trainingCommunity-based vocational servicesWeekly support groupsCognitive remediationCognitive trainingExecutive functionWork outcomesRemediation programVocational outcomesCommunity mental health centerMental health centersCognitive impairmentSixth quarterVocational servicesNet trainingTherapy outcomeSupport groupsCompetitive employmentSchizophreniaRehabilitation methodsSchizoaffective patientsEmployment programsTraining
2007
A pilot study of a weight management program with food provision in schizophrenia
Jean-Baptiste M, Tek C, Liskov E, Chakunta UR, Nicholls S, Hassan AQ, Brownell KD, Wexler BE. A pilot study of a weight management program with food provision in schizophrenia. Schizophrenia Research 2007, 96: 198-205. PMID: 17628437, DOI: 10.1016/j.schres.2007.05.022.Peer-Reviewed Original ResearchConceptsWeight lossSignificant medical risksMeaningful weight lossWeight loss programWeight management programSevere mental illnessSerious medical problemLifestyle modificationComorbid obesityLoss programPilot trialGeneral populationMetabolic indicesCognitive impairmentMental illnessMedical riskMedical problemsWeight gainObesityPilot studySpecific populationsSchizophreniaBehavioral programHealthy foodsReplacement program
2005
Effects of Cigarette Smoking on Spatial Working Memory and Attentional Deficits in Schizophrenia: Involvement of Nicotinic Receptor Mechanisms
Sacco KA, Termine A, Seyal A, Dudas MM, Vessicchio JC, Krishnan-Sarin S, Jatlow PI, Wexler BE, George TP. Effects of Cigarette Smoking on Spatial Working Memory and Attentional Deficits in Schizophrenia: Involvement of Nicotinic Receptor Mechanisms. JAMA Psychiatry 2005, 62: 649-659. PMID: 15939842, DOI: 10.1001/archpsyc.62.6.649.Peer-Reviewed Original ResearchConceptsVisuospatial working memoryWorking memoryAttentional deficitsCognitive deficitsOvernight abstinenceContinuous Performance Test scoresSpatial working memoryOutpatient mental health centersPerformance test scoresCognitive enhancementCPT performanceNeuropsychological assessmentSmoking reinstatementTobacco cravingControl smokersTest scoresCounterbalanced mannerMental health centersCognitive impairmentReinstatementSubjective effectsNicotine dependenceCigarette smokingDeficitsNicotinic receptor mechanisms