2002
Reticulated platelets predict platelet count recovery following chemotherapy
Wang C, Smith BR, Ault KA, Rinder HM. Reticulated platelets predict platelet count recovery following chemotherapy. Transfusion 2002, 42: 368-374. PMID: 11961244, DOI: 10.1046/j.1537-2995.2002.00040.x.Peer-Reviewed Original ResearchConceptsPlatelet count recoveryPercentage of RPProphylactic platelet transfusionsCount recoveryPlatelet transfusionsPlatelet recoveryStress thrombopoiesisPlatelet count increaseIdiopathic thrombocytopenic purpuraPlatelet count nadirsChemotherapy-induced thrombocytopeniaNegative predictive valueEvaluable patientsMarrow suppressionThrombocytopenic purpuraChemotherapy patientsThrombocytopenia patientsLower percentagePatientsPredictive valueReproducible indexThrombocytopeniaTransfusionChemotherapyIncreased percentage
1999
Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation
Rinder CS, Rinder HM, Smith MJ, Tracey JB, Fitch J, Li L, Rollins SA, Smith BR. Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation. Journal Of Thoracic And Cardiovascular Surgery 1999, 118: 460-466. PMID: 10469960, DOI: 10.1016/s0022-5223(99)70183-2.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalBlood PlateletsComplement ActivationComplement C3aComplement C8Complement Membrane Attack ComplexEnzyme-Linked Immunosorbent AssayExtracorporeal CirculationFlow CytometryHumansLeukocyte CountLeukocyte ElastaseMacrophage-1 AntigenNeutrophil ActivationNeutrophilsPlatelet ActivationPlatelet CountP-SelectinReference ValuesConceptsNeutrophil activationExtracorporeal circuitExtracorporeal circulationLeukocyte activationMembrane attack complexPlatelet activationC5b-9C5b-9 generationAttack complexC5b-9 formationMembrane attack complex formationPlatelet CD62PControl circulationCardiopulmonary bypassLate complement componentsPlatelet countMonocyte countInhibits plateletSelective blockadeLoss of monocytesExtracorporeal modelSC5b-9Complement activationComplement componentsCellular activation
1994
Noninvasive measurement of platelet kinetics in normal and hypertensive pregnancies
Rinder H, Bonan J, Anandan S, Rinder C, Rodrigues P, Smith B. Noninvasive measurement of platelet kinetics in normal and hypertensive pregnancies. American Journal Of Obstetrics And Gynecology 1994, 170: 117-122. PMID: 8296812, DOI: 10.1016/s0002-9378(94)70395-7.Peer-Reviewed Original ResearchConceptsPregnancy-induced hypertensionNormal pregnancyPlatelet countPlatelet kineticsImmune platelet destructionSerum antiplatelet antibodiesPlatelet-associated immunoglobulinsLarge prospective studiesNormal nonpregnant womenOnset of symptomsPlatelet productionHypertensive pregnanciesAntiplatelet antibodiesNonpregnant womenClinical courseNulliparous womenWeeks' gestationPlatelet destructionProspective studyPregnant womenClinical signsPlatelet valuesSerial measurementsBlood samplesPlatelet decrease
1993
Reticulated platelets in the evaluation of thrombopoietic disorders.
Rinder HM, Munz UJ, Ault KA, Bonan JL, Smith BR. Reticulated platelets in the evaluation of thrombopoietic disorders. Archives Of Pathology & Laboratory Medicine 1993, 117: 606-10. PMID: 8503732.Peer-Reviewed Original ResearchConceptsImmune platelet destructionImmune thrombocytopeniaPlatelet destructionNormal subjectsImmune thrombocytopenic purpuraThird of patientsSubset of patientsPlatelet determinationAbsence of megakaryocytesPlatelet-associated IgGChemotherapy-induced thrombocytopeniaInvasive diagnostic testsPeripheral blood plateletsFlow cytometric assayIgG levelsThrombocytopenic purpuraReticulated plateletsImmune destructionPlatelet valuesPatientsPlatelet IgGBone marrowThrombocytopeniaIgG dataLaboratory diagnosis