Boby Mathew
Associate Research ScientistCards
About
Research
Publications
2026
Cell-type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling
Plucińska K, Wayne C, Sanford H, Mathew B, Ropek N, Adaniya S, Model C, Gómez-Banoy N, Morozova K, Cao X, Friedman J, Loh K, Cohen P, Vinogradova E. Cell-type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling. Cell Reports 2026, 45: 117507. PMID: 42284144, DOI: 10.1016/j.celrep.2026.117507.Peer-Reviewed Original ResearchBeta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development
Garcia C, Venkat A, McQuaid D, Agabiti S, Tong A, Mathew B, Cardone R, Starble R, Ruiz C, Zheng C, Sogunro A, Jacox J, Loh K, Kibbey R, Krishnaswamy S, Muzumdar M. Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development. Nature Communications 2026, 17: 3292. PMID: 41760660, PMCID: PMC13066563, DOI: 10.1038/s41467-026-69821-2.Peer-Reviewed Original ResearchThis study investigates how obesity-induced cholecystokinin (CCK) expression in pancreatic beta cells drives pancreatic cancer development by altering cellular signaling within the environment of arising tumors, suggesting potential therapeutic targets.
2022
RhoC in association with TET2/WDR5 regulates cancer stem cells by epigenetically modifying the expression of pluripotency genes
Thomas P, Srivastava S, Udayashankara A, Damodaran S, Yadav L, Mathew B, Suresh S, Mandal A, Srikantia N. RhoC in association with TET2/WDR5 regulates cancer stem cells by epigenetically modifying the expression of pluripotency genes. Cellular And Molecular Life Sciences 2022, 80: 1. PMID: 36469134, PMCID: PMC11073244, DOI: 10.1007/s00018-022-04645-z.Peer-Reviewed Original ResearchDeciphering Spatial Protein–Protein Interactions in Brain Using Proximity Labeling
Mathew B, Bathla S, Williams KR, Nairn AC. Deciphering Spatial Protein–Protein Interactions in Brain Using Proximity Labeling. Molecular & Cellular Proteomics 2022, 21: 100422. PMID: 36198386, PMCID: PMC9650050, DOI: 10.1016/j.mcpro.2022.100422.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsTranscriptome profiling of barley and tomato shoot and root meristems unravels physiological variations underlying photoperiodic sensitivity
Schneider M, Vedder L, Oyiga B, Mathew B, Schoof H, Léon J, Naz A. Transcriptome profiling of barley and tomato shoot and root meristems unravels physiological variations underlying photoperiodic sensitivity. PLOS ONE 2022, 17: e0265981. PMID: 36095002, PMCID: PMC9467324, DOI: 10.1371/journal.pone.0265981.Peer-Reviewed Original ResearchNeuralLasso: Neural Networks Meet Lasso in Genomic Prediction
Mathew B, Hauptmann A, Léon J, Sillanpää M. NeuralLasso: Neural Networks Meet Lasso in Genomic Prediction. Frontiers In Plant Science 2022, 13: 800161. PMID: 35574107, PMCID: PMC9100816, DOI: 10.3389/fpls.2022.800161.Peer-Reviewed Original ResearchPlasma Apolipoprotein-AIV Downregulated in Patients with Major Depressive Disorder having Suicidal Ideation Compared to those without Suicidal Ideation
Mathew B, Srinivasan K, Pradeep J, Thomas T, Mandal A. Plasma Apolipoprotein-AIV Downregulated in Patients with Major Depressive Disorder having Suicidal Ideation Compared to those without Suicidal Ideation. Current Proteomics 2022, 19: 226-231. DOI: 10.2174/1570164618666211104151005.Peer-Reviewed Original Research
2021
Genomic regions associated with physiological, biochemical and yield-related responses under water deficit in diploid potato at the tuber initiation stage revealed by GWAS
Díaz P, Sarmiento F, Mathew B, Ballvora A, Vásquez T. Genomic regions associated with physiological, biochemical and yield-related responses under water deficit in diploid potato at the tuber initiation stage revealed by GWAS. PLOS ONE 2021, 16: e0259690. PMID: 34748612, PMCID: PMC8575265, DOI: 10.1371/journal.pone.0259690.Peer-Reviewed Original ResearchImportance of correcting genomic relationships in single-locus QTL mapping model with an advanced backcross population
Mathew B, Léon J, Dadshani S, Pillen K, Sillanpää M, Naz A. Importance of correcting genomic relationships in single-locus QTL mapping model with an advanced backcross population. G3: Genes, Genomes, Genetics 2021, 11: jkab105. PMID: 33822941, PMCID: PMC8495747, DOI: 10.1093/g3journal/jkab105.Peer-Reviewed Original ResearchDetection of breeding signatures in wheat using a linkage disequilibrium-corrected mapping approach
Dadshani S, Mathew B, Ballvora A, Mason A, Léon J. Detection of breeding signatures in wheat using a linkage disequilibrium-corrected mapping approach. Scientific Reports 2021, 11: 5527. PMID: 33750919, PMCID: PMC7970893, DOI: 10.1038/s41598-021-85226-1.Peer-Reviewed Original Research
Get In Touch
Contacts
Email