Betsy Schulman, PhD
Associate Research ScientistCards
About
Research
Publications
2026
Nav1.8 Variant I206M as a Latent Susceptibility Factor in Postaxotomy Ocular Pain
Ghovanloo M, Effraim P, Tyagi S, Aldrich A, Yuan J, Schulman B, Jacobs D, Dib-Hajj S, Waxman S. Nav1.8 Variant I206M as a Latent Susceptibility Factor in Postaxotomy Ocular Pain. Neurology Genetics 2026, 12: e200367. PMID: 41868096, PMCID: PMC13004580, DOI: 10.1212/nxg.0000000000200367.Peer-Reviewed Original Research
2025
Nav1.8: Intrinsic limits on the functional effect of abrogation in DRG neurons
Vasylyev D, Zhao P, Schulman B, Waxman S. Nav1.8: Intrinsic limits on the functional effect of abrogation in DRG neurons. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2507342122. PMID: 41004224, PMCID: PMC12501176, DOI: 10.1073/pnas.2507342122.Peer-Reviewed Original ResearchCorrection of sodium channel mutations in sensory neurons reverses aberrant properties
Shim J, Tanaka B, Taub D, Mis M, Schulman B, Snavely A, Cheng Y, Laedermann C, Buttermore E, Ren A, Hermawan C, Dou D, Kawaguchi R, Geschwind D, Dib-Hajj S, Waxman S, Woolf C. Correction of sodium channel mutations in sensory neurons reverses aberrant properties. Brain 2025, 148: 3718-3726. PMID: 40279376, PMCID: PMC13369953, DOI: 10.1093/brain/awaf155.Peer-Reviewed Original Research
2024
TRPM8 Mutations Associated With Persistent Pain After Surgical Injury of Corneal Trigeminal Axons
Ghovanloo M, Effraim P, Tyagi S, Aldrich A, Cheng X, Yuan J, Schulman B, Jacobs D, Dib-Hajj S, Waxman S. TRPM8 Mutations Associated With Persistent Pain After Surgical Injury of Corneal Trigeminal Axons. Neurology Genetics 2024, 10: e200206. PMID: 39555137, PMCID: PMC11567650, DOI: 10.1212/nxg.0000000000200206.Peer-Reviewed Original ResearchInterplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain
Vasylyev D, Zhao P, Schulman B, Waxman S. Interplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain. Journal Of General Physiology 2024, 156: e202413596. PMID: 39378238, PMCID: PMC11465073, DOI: 10.1085/jgp.202413596.Peer-Reviewed Original Research
2023
Nav1.7 P610T mutation in two siblings with persistent ocular pain after corneal axon transection: impaired slow inactivation and hyperexcitable trigeminal neurons
Ghovanloo M, Effraim P, Yuan J, Schulman B, Jacobs D, Dib-Hajj S, Waxman S. Nav1.7 P610T mutation in two siblings with persistent ocular pain after corneal axon transection: impaired slow inactivation and hyperexcitable trigeminal neurons. Journal Of Neurophysiology 2023, 129: 609-618. PMID: 36722722, PMCID: PMC9988530, DOI: 10.1152/jn.00457.2022.Peer-Reviewed Original ResearchNav1.7-P610T mutation in 2 siblings with persistent ocular pain after corneal axon transection: impaired slow-inactivation and hyperexcitable trigeminal neurons
J Neurophysiol. 2023 Feb 1. doi: 10.1152/jn.00457.2022. Online ahead of print.Peer-Reviewed Original Research In Press
2021
KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience
Yuan JH, Estacion M, Mis MA, Tanaka BS, Schulman BR, Chen L, Liu S, Dib-Hajj FB, Dib-Hajj SD, Waxman SG. KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience. Brain Communications 2021, 3: fcab212-. PMID: 34557669, PMCID: PMC8454204, DOI: 10.1093/braincomms/fcab212.Peer-Reviewed Original Research
2020
Genomic analysis of 21 patients with corneal neuralgia after refractive surgery
Yuan JH, Schulman BR, Effraim PR, Sulayman DH, Jacobs DS, Waxman SG. Genomic analysis of 21 patients with corneal neuralgia after refractive surgery. PAIN Reports 2020, 5: e826. PMID: 32766464, PMCID: PMC7390595, DOI: 10.1097/pr9.0000000000000826.Peer-Reviewed Original Research
2019
A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain
Huang J, Estacion M, Zhao P, Dib-Hajj FB, Schulman B, Abicht A, Kurth I, Brockmann K, Waxman SG, Dib-Hajj SD. A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain. Frontiers In Neuroscience 2019, 13: 918. PMID: 31551682, PMCID: PMC6733892, DOI: 10.3389/fnins.2019.00918.Peer-Reviewed Original Research
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