Modern Chemotherapy Mitigates Adverse Prognostic Effect of Regional Nodal Metastases in Stage IV Colorectal Cancer
Thomay AA, Nagorney DM, Cohen SJ, Sigurdson ER, Truty MJ, Burtness B, Hall MJ, Chun YS. Modern Chemotherapy Mitigates Adverse Prognostic Effect of Regional Nodal Metastases in Stage IV Colorectal Cancer. Journal Of Gastrointestinal Surgery 2013, 18: 69-74. PMID: 24002765, DOI: 10.1007/s11605-013-2329-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCamptothecinColorectal NeoplasmsFemaleHepatectomyHumansIrinotecanKaplan-Meier EstimateLiver NeoplasmsLung NeoplasmsLymph NodesLymphatic MetastasisMaleMiddle AgedNeoplasm StagingOrganoplatinum CompoundsOvarian NeoplasmsOxaliplatinPeritoneal NeoplasmsPrognosisRetrospective StudiesYoung AdultConceptsStage IV colorectal cancerLymph node ratioPositive regional nodesRegional lymph nodesRegional nodal metastasesColorectal cancerPositive nodesOverall survivalRegional nodesLiver metastasesLymph nodesNodal metastasisPrognostic significanceModern chemotherapyMetastatic regional lymph nodesStage IV diseasePrimary tumor resectionTertiary referral centerDate of diagnosisAdverse prognostic effectMedian OSPerioperative oxaliplatinReferral centerPrognostic factorsRetrospective review