2024
Clinical Course of Isolated Recurrent, Persistent Complex Perianal Fistulas without Luminal Crohn’s Disease: A Multicenter Case Series of 24 Patients
Fiske H, Tse C, Al-Bawardy B, Magavi P, Konijeti G, Mao E, Fine S, Parian A, Lazarev M, Shah S. Clinical Course of Isolated Recurrent, Persistent Complex Perianal Fistulas without Luminal Crohn’s Disease: A Multicenter Case Series of 24 Patients. Crohn's & Colitis 360 2024, otae065. DOI: 10.1093/crocol/otae065.Peer-Reviewed Original ResearchComplex perianal fistulasMulticenter case seriesPerianal fistulasIntensive surgical interventionClinical courseCrohn's diseaseCase seriesSurgical interventionPresumptive diagnosis of Crohn's diseaseClinical course of patientsEvidence of inflammatory bowel diseaseRetrospective multicenter case seriesPresentation of Crohn's diseaseLuminal Crohn's diseaseCourse of patientsOutcomes of patientsDiagnosis of Crohn's diseaseMedical-surgical approachInflammatory bowel diseaseComplex fistulasLuminal inflammationFistula closureCryptoglandular fistulasSurgical therapyBiologic therapy
2017
Endoscopic muscle biopsy sampling of the duodenum and rectum: a pilot survival study in a porcine model to detect myenteric neurons
Rajan E, Al-Bawardy B, Gostout CJ, Wong Kee Song LM, Deters JL, Knipschield MA, Bernard CE, Farrugia G. Endoscopic muscle biopsy sampling of the duodenum and rectum: a pilot survival study in a porcine model to detect myenteric neurons. Gastrointestinal Endoscopy 2017, 87: 600-606. PMID: 28734992, PMCID: PMC5775930, DOI: 10.1016/j.gie.2017.07.023.Peer-Reviewed Original ResearchConceptsMuscle biopsy samplingProtein gene product 9.5Myenteric neuronsMuscularis propriaGene product 9.5Biopsy samplingSnare electrocauteryUpper endoscopyProduct 9.5Scope clipDuodenal wallBand ligation techniqueFunctional bowel disordersSlow transit constipationProcedural adverse eventsRectal muscularis propriaIntermuscular layerAdverse eventsBowel disordersClinical courseMotility disordersSmall bowelSurgical approachTissue diagnosisPreclinical studies